支架长度、过渡长度和冠状动脉过度扩张的影响

Naresh K. C. Selvarasu, D. Tafti
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摘要

在这项工作中,我们研究了在曲率和扭转动态变化的影响下,支架长度、支架过渡长度和支架过膨胀的影响。我们的目的是了解这三个参数对局部血流动力学的影响。对具有生理相关流动参数的简化冠状动脉进行了三维、时空分辨计算流体动力学(CFD)模拟,模拟了具有移动壁面边界和流固耦合的脉动流动。采用支架段弹性模量变化为5的可变形墙体移动模型作为基准控制案例。从局部血流动力学和管壁剪切应力的变化可以看出,支架长度越小,充分覆盖病变部位,支架过渡长度越长,支架段过扩张越小,支架内动脉的血流状况就越好。
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Effects of stent length, transition length and overexpansion in stented coronary arteries
In this work, we study the effect of stent length, stent transition length and stent overexpansion under the influence of dynamic changes in curvature and torsion. It is our objective to understand the influence of these three parameters on local hemodynamics. Three-dimensional, spatiotemporally resolved computational fluid dynamics (CFD) simulations of pulsatile flow with moving wall boundaries and fluid structure interaction were carried out for a simplified coronary artery with physiologically relevant flow parameters. A model with moving deformable walls with an elastic modulus change of five in the stented section is used as the baseline control case. From the local hemodynamics and wall shear stress changes, it can be concluded that the smaller stent length that adequately covers the lesion site, higher transition length and lower overexpansion of the stented section would lead to improved flow conditions in the stented artery.
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