静电纺丝法制备中空生物活性玻璃纳米纤维

Q1 Materials Science Biomedical Glasses Pub Date : 2015-11-03 DOI:10.1515/bglass-2015-0013
Botao Song, Liang Wu, Chengtie Wu, Jiang Chang
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引用次数: 10

摘要

本文采用单喷嘴静电纺丝法制备了中空生物活性玻璃(BG)纳米纤维。通过SEM和TEM对制备的空心BG纳米纤维的形貌进行了观察,结果表明BG纳米纤维具有连续中空的内部结构。将中空BG纳米纤维置于模拟体液(SBF)中孵育,考察其磷灰石矿化能力,结果表明,孵育6 h后,中空BG纳米纤维表面出现花状磷灰石,傅里叶变换红外(FTIR)结果进一步证实了磷灰石的形成。结果表明,由于其独特的中空结构和生物活性,空心BG纳米纤维可用于药物输送和骨再生。
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Preparation of hollow bioactive glass nanofibers by a facile electrospinning method
Abstract In this communication, hollow bioactive glass (BG) nanofibers were fabricated via a single-nozzle electrospinning method. The morphology of the prepared hollow BG nanofibers was observed by SEM and TEM, and the results showed that BG nanofibers had a continuous hollow interior. The hollow BG nanofibers were incubated in simulated body fluid (SBF) to investigate their apatitemineralization ability, and the result showed that after incubation for 6 h a flower-like apatite was observed on the surface of hollowBGnanofibers, and the Fourier transform infrared (FTIR) result further confirmed the formation of apatite. The results suggested that hollow BG nanofibers could be used for drug delivery and bone regeneration applications due to their unique hollow structure and bioactivity.
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来源期刊
Biomedical Glasses
Biomedical Glasses Materials Science-Surfaces, Coatings and Films
自引率
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审稿时长
17 weeks
期刊介绍: Biomedical Glasses is an international Open Access-only journal covering the field of glasses for biomedical applications. The scope of the journal covers the science and technology of glasses and glass-based materials intended for applications in medicine and dentistry. It includes: Chemistry, physics, structure, design and characterization of biomedical glasses Surface science and interactions of biomedical glasses with aqueous and biological media Modeling structure and reactivity of biomedical glasses and their interfaces Biocompatibility of biomedical glasses Processing of biomedical glasses to achieve specific forms and functionality Biomedical glass coatings and composites In vitro and in vivo evaluation of biomedical glasses Glasses and glass-ceramics in engineered regeneration of tissues and organs Glass-based devices for medical and dental applications Application of glasses and glass-ceramics in healthcare.
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