Cramp Fasciculation Syndrome in Athletes: A Report of Two Cases

Muscle Cramps are a common chief complaint encountered in sports medicine and primary care clinics. Cramping can be debilitating and significantly impact a person’s quality of life and athletic performance. Current theories generally categorize cramps as those caused by overexertion of a specific muscle group or due to sodium deficiencies. In patients that have associated fasciculations, the diagnosis of Cramp Fasciculation Syndrome (CFS) should be considered as the pathophysiology and treatment is different. Cramp Fasciculation syndrome (CFS) is a chronic, benign condition characterized by fasciculations and significant muscle cramps. The cramps are typically triggered by exertion and are due to peripheral nerve hyper-excitability rather than muscle fatigue or electrolyte deficiency. Examination is typically normal with no evidence of motor weakness or atrophy. Anticonvulsants such as Gabepentin has been shown to reduce cramping.