Real-world experience with tramadol plus dexketoprofen fixed-dose combination in postoperative pain management: A series of case studies from Asia

Background: Early and effective treatment of postoperative pain is vital for minimizing pain severity and optimizing patient outcomes and satisfaction. The efficacy and tolerability data of tramadol 75 mg plus dexketoprofen 25 mg fixed-dose combination (TRAM/DKP FDC) are reported in clinical trials but the data on real-world experience in postoperative pain management in the Asian population is limited. Objectives: This series of case studies reviews clinicians’ experience and outcomes of postoperative pain management in Asian patients using a TRAM/DKP FDC in the real-world setting. Methods: Clinicians compiled, shared and discussed case studies of their experience using a TRAM/DKP FDC during two case studies expert meetings. A total of 13 case studies were shared across orthopaedic, soft tissue and laparoscopic surgery. Results: All cases reported well-tolerated postoperative pain management with good pain relief with TRAM/DKP FDC. Conclusions: TRAM/DKP FDC is an effective and well-tolerated option for the management of acute moderate-to-severe postoperative pain in Asian patients.