生物类似药在类风湿关节炎中的作用——从研发到销售的过程和世界趋势

H. Matsuno
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引用次数: 0

摘要

图1和图2显示了目前在日本上市的用于类风湿性关节炎(RA)的先进治疗药物的销售趋势。2003年英夫利昔单抗上市后,生物制品大量进入市场,出现了不同作用机制和给药方案的生物制品(与国外不同,日本未批准使用美罗华治疗RA)。第一个生物制品在日本上市10年后,Janus激酶抑制剂的销售得到了促进,生物仿制药(BSs)也积极上市。
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Role of biosimilars in rheumatoid arthritis - Process from R & D to marketing and trends in the world
Figures 1 and 2 shows the trend of the sale of advanced therapeutic drugs for rheumatoid arthritis (RA) currently available commercially in Japan. After the release of infliximab in 2003, biological products were introduced to the market with great frequency, and biological products with different mechanisms of action and dosing regimens became available (the use of rituximab for RA is not approved in Japan, unlike in overseas countries). Ten years after the release of the first biological product in Japan, the sale of Janus kinase inhibitors was promoted, and biosimilars (BSs) were also actively marketed.
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