模块化假体重建胫骨远端原发性骨肿瘤10例

W. Mugla, H. Bauer, J. Vogel, K. Hosking, N. Campbell, T. Hilton
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引用次数: 0

摘要

背景:膝下截肢(BKA)是胫骨远端良性侵袭性和恶性骨肿瘤最安全的治疗方法,具有良好的肿瘤学和功能效果。然而,在残肢保留可行且不能接受截肢的特定患者中,可以考虑使用远端胫骨置换术(DTR)进行残肢保留。本研究旨在介绍后一种治疗方法在我单位使用的肿瘤学和功能结果。方法:对2005年1月1日至2019年1月31日期间因原发性骨肿瘤(良性、侵袭性或恶性)接受模块化DTR的所有10例患者进行回顾性文件夹回顾。女性6例,平均年龄31岁(12 ~ 75岁)。5例为骨巨细胞瘤,4例为骨肉瘤,1例为低级别软骨肉瘤。骨肉瘤患者术前均行新辅助化疗。功能由肌肉骨骼肿瘤协会(MSTS)评分评估。结果:2例患者局部复发,另1例患者术后3年死于转移。在平均3年的随访中,其余8例患者的平均MSTS评分为83%(67-93%)。放射学上没有松动迹象,也没有翻修手术。结论:胫骨远端置换术治疗原发性骨肿瘤是一种安全的治疗选择。证据等级:四级
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Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients
BACKGROUND: Below-knee amputation (BKA) is the safest treatment for benign aggressive and malignant bone tumours of the distal tibia, yielding good oncological and functional results. However, in selected patients where limb salvage is feasible and amputation unacceptable to the patient, limb salvage using a distal tibial replacement (DTR) can be considered. This study aims to present the oncological and functional results of the use of the latter treatment method in our unit. METHODS: A retrospective folder review was performed for all ten patients who received a modular DTR between 1 January 2005 and 31 January 2019 for a primary bone tumour, either benign aggressive or malignant. Six were female and the mean age was 31 (12-75) years. There were five patients with giant cell tumour of bone, four with osteosarcoma and one with a low-grade chondrosarcoma. The patients with osteosarcoma had neoadjuvant chemotherapy before surgery. Function was assessed by the Musculoskeletal Tumor Society (MSTS) score. RESULTS: Two patients had local recurrence treated with a BKA and one other patient died of metastases three years postoperatively. At a mean follow-up of three years, the remaining eight patients had a mean MSTS score of 83% (67-93%). There were no radiological signs of loosening, and no revision surgeries. CONCLUSION: Endoprosthetic replacement of the distal tibia for primary bone tumours can be a safe treatment option in very selected cases. Level of evidence: Level 4
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来源期刊
SA Orthopaedic Journal
SA Orthopaedic Journal Medicine-Orthopedics and Sports Medicine
CiteScore
0.40
自引率
0.00%
发文量
17
审稿时长
6 weeks
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