腰椎管狭窄患者维生素d缺乏的频率及其与肥胖、抑郁和疼痛强度的关系:一项横断面研究

IF 0.6 4区 医学 Q4 NUTRITION & DIETETICS Revista De Nutricao-brazilian Journal of Nutrition Pub Date : 2022-01-01 DOI:10.1590/1678-9865202235e220020
Cansu MEMİÇ-İNAN, Pınar SÖKÜLMEZ-KAYA, Semih Akar
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引用次数: 0

摘要

【摘要】目的本研究旨在确定腰椎管狭窄症患者维生素D缺乏的频率,并确定维生素D水平与肥胖、抑郁和疼痛强度之间的关系。方法对诊断为腰椎管狭窄症的69例患者(男32例,女37例)进行研究。用放射免疫法测定受试者的25(OH)D水平。此外,还评估了骨代谢状态,包括骨矿物质密度和骨转换标志物。采用Beck抑郁量表测定患者的抑郁状态,采用McGill Melzack疼痛问卷测定患者的疼痛强度。结果以p<0.05的显著性水平进行评价。结果76.8%的患者存在维生素D缺乏症(<20 ng/mL)。二元logistic回归分析显示:1)体质指数较高的患者出现维生素D缺乏症的频率显著较高(OR 3.197, 95% CI 1.549-6.599);2) Beck抑郁评分较高(OR 1.817, 95% CI 1.027 ~ 3.217);3)女性多于男性(OR 1.700, 95% CI 0.931-3.224) (p<0.05)。结论本研究中,腰椎管狭窄症患者普遍缺乏维生素D。此外,肥胖、抑郁和女性个体缺乏维生素D的风险更高。
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Frequency of vitamin d deficiency in patients with lumbar spinal stenosis and its relationship with obesity, depression, and pain intensity: a cross-sectional study
ABSTRACT Objective This study was conducted to determine the frequency of vitamin D deficiency in patients with lumbar spinal stenosis and to define the relationship between vitamin D levels and obesity, depression, and pain intensity. Methods This study was conducted with 69 patients (Male = 32, Female = 37) diagnosed with lumbar spinal stenosis. The participants’ 25(OH)D levels were measured by radioimmunoassay. In addition, bone metabolic status, including bone mineral density and bone turnover markers, was also evaluated. The Beck Depression Inventory was used to determine the depression statuses of the patients, while the McGill Melzack Pain Questionnaire was administered to measure pain intensity. The results were evaluated at a significance level of p<0.05. Results Vitamin D deficiency (<20 ng/mL) was found in 76.8% of the patients. Binary logistic regression analysis showed a significantly higher frequency of vitamin D deficiency in patients who: 1) had higher body mass indexes (OR 3.197, 95% CI 1.549-6.599); 2) fared higher in Beck’s depression score (OR 1.817, 95% CI 1.027–3.217); and 3) were female rather than male (OR 1.700, 95% CI 0.931-3.224) (p<0.05). Conclusion In this study, vitamin D deficiency was prevalent in lumbar spinal stenosis patients. In addition, obese, depressed, and female individuals have higher risks of vitamin D deficiency.
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来源期刊
CiteScore
1.20
自引率
12.50%
发文量
24
审稿时长
6-12 weeks
期刊介绍: Revista de Nutrição is former Revista de Nutrição da Puccamp, founded in 1988. It is a bimonthly publication every four months and it is of responsibility of the Centro de Ciências da Vida, da Pontifícia Universidade Católica de Campinas . It publishes articles that contribute to the study of Nutrition in its many sub-areas and interfaces; and is open to contributions of the national and international scientific communities.
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