肉毒杆菌毒素与语音治疗对严重吞咽困难患者的益处

Fernanda Teixeira Menezes, Katia Alonso Rodrigues, Isabel Neto, Brasília Maria Chiari, Dayse Manrique, Maria Inês Rebelo Gonçalves
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引用次数: 2

摘要

病例报告的目的是描述肉毒杆菌毒素注射到唾液腺与吞咽治疗相关的严重吞咽困难患者的好处。对5例单纯采用替代喂养的神经系统患者(男4名,女1名,年龄在17 ~ 70岁之间)的病历进行分析。4例患者行气管造口术。纳入标准为严重的吞咽困难,临床表现为流口水和/或唾液,并伴有明显的唾液误吸,限制了吞咽康复的改善。收集注射肉毒杆菌毒素干预前后的数据,包括口咽结构(嘴唇、舌头和脸颊)的活动度和强度、喉抬高、吞咽困难的严重程度、是否使用替代管喂养和气管造口术。吞咽治疗后,4名患者的嘴唇、舌头、脸颊和喉部的活动性和力量有所改善。4例患者出现功能性吞咽,其中1例患者吞咽困难严重程度发生改变。因此,大多数患者都能接受单独的口服喂养,只有1例患者仍然接受混合喂养,即胃造口和糊状的口服喂养。所有气管造口患者均取出气管造口套管。研究表明,所描述的治疗有助于吞咽康复,重新引入口服喂养,并撤回气管切开术插管。
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Benefícios da aplicação de toxina botulínica associada à fonoterapia em pacientes disfágicos graves
Case report with the aim to characterize the benefits of botulinum toxin injection into salivary glands in association with swallowing therapy in patients with severe dysphagia. The medical records of five neurological patients (four male and one female, aged between 17 and 70 years) who exclusively used alternative feeding were analyzed. Four patients were tracheostomized. Inclusion criterion was to present severe dysphagia associated to clinical manifestations of drooling and/or sialorrhea with significant aspiration of saliva, restricting the improvement in swallowing rehabilitation. Data were collected before and after intervention associated with botulinum toxin injection, regarding the following aspects: mobility and strength of oropharyngeal structures (lips, tongue and cheeks), laryngeal elevation, severity degree of dysphagia, use of alternative tube feeding and tracheostomy. After swallowing therapy, four patients showed improvement in mobility and strength of the lips, tongue, cheeks and larynx. Four patients presented functional swallowing and one of them modified had the severity degree of dysphagia changed. Therefore, most patients were able to receive exclusive oral feeding, and only one remained on mixed feeding, that is, gastrostomy and oral feeding with pasty consistence. All tracheostomized patients had the tracheostomy cannula removed. The study showed that the treatment described contributed to swallowing rehabilitation, reintroduction of oral feeding, and withdrawal of the tracheostomy cannula.
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