{"title":"含碳酸氢钠的氟化牙膏对变形链球菌计数、致酸性和牙菌斑组成的影响","authors":"Rosa Fernanda Ignácio, P. E. C. Peres, J. Cury","doi":"10.1590/S0103-06631999000100010","DOIUrl":null,"url":null,"abstract":"This investigation evaluated the effect of a fluoride baking soda-containing dentifrice on mutans streptococci counting, acidogenicity and composition of dental plaque. Twenty-three volunteers brushing their teeth 3 times a day, tested 3 formulations of fluoride (1500 ppm F), containing or sodium bicarbonate (12%) associated with calcium carbonate (CARB/BICAR), or calcium carbonate (CARBONATE), or silica (SILICA), in a double blind crossover trial, done in 3 phases of 30 days each. On the 28th day, 8-10 hours after the last brushing, a counting of mutans streptococci in saliva (SMS) was made. On the 30th day (after 48 hours during which the subjects were instructed to rinse with a slurry of toothpaste/water 3 times a day and sucrose 10% 6 times a day), the effect was analyzed in dental plaque, 10-12 hours after the last rinse: a) mutans streptococci (PMS); b) polysaccharide alkali-soluble (ASP); c) acid-soluble F (ASF) and d) pH in T0 (T0), 5 min. after cariogenic challenge (T5), calculating DpH (T0 - T5). The results (mean + SE) according to the treatments with dentifrices SILICA, CARBONATE and CARB/BICAR, were respectively: 1) SMS (x 106 UFC/mL saliva) = 11.43 + 7.62 A; 2,33 + 1.04 A; 2.07 + 1.10 A; 2) PMS (x 106 UFC/mg) = 0.099 + 0.095 A; 0.027 + 0.018 A; 0.007 + 0.003 A; 3) ASP (mg/mg) = 6.89 + 0.62 AC; 8.46 + 0.80 AB; 6.11 + 0.59 C; 4) ASF (mg/g) = 36.67 + 10.10 A; 48.12 + 19.23 A; 52.21 + 15.12 A; 5) T0 = 6.72 + 0.12 A; 6.88 + 0.13 A; 6.65 + 0.11 A; 6) T5 = 5.61 + 0.13 A; 5.71 + 0.13 A; 5.70 + 0.12 A; 7) DpH = 1.12 + 0.11 A; 1.17 + 0.11 A; 0.95 + 0.10 A. Means followed by the same letter do not differ significantly (P < 0.05). The data show that although the baking soda-containing dentifrice demonstrated, collectively, a trend to influence positively the various factors of dental caries, it did not differ significantly from SILICA and CARBONATE dentifrices.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"13 1","pages":"43-49"},"PeriodicalIF":0.0000,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"9","resultStr":"{\"title\":\"Efeito de um dentifrício fluoretado contendo bicarbonato de sódio na contagem de estreptococos do grupo mutans, acidogenicidade e composição da placa dental\",\"authors\":\"Rosa Fernanda Ignácio, P. E. C. Peres, J. Cury\",\"doi\":\"10.1590/S0103-06631999000100010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This investigation evaluated the effect of a fluoride baking soda-containing dentifrice on mutans streptococci counting, acidogenicity and composition of dental plaque. Twenty-three volunteers brushing their teeth 3 times a day, tested 3 formulations of fluoride (1500 ppm F), containing or sodium bicarbonate (12%) associated with calcium carbonate (CARB/BICAR), or calcium carbonate (CARBONATE), or silica (SILICA), in a double blind crossover trial, done in 3 phases of 30 days each. On the 28th day, 8-10 hours after the last brushing, a counting of mutans streptococci in saliva (SMS) was made. On the 30th day (after 48 hours during which the subjects were instructed to rinse with a slurry of toothpaste/water 3 times a day and sucrose 10% 6 times a day), the effect was analyzed in dental plaque, 10-12 hours after the last rinse: a) mutans streptococci (PMS); b) polysaccharide alkali-soluble (ASP); c) acid-soluble F (ASF) and d) pH in T0 (T0), 5 min. after cariogenic challenge (T5), calculating DpH (T0 - T5). The results (mean + SE) according to the treatments with dentifrices SILICA, CARBONATE and CARB/BICAR, were respectively: 1) SMS (x 106 UFC/mL saliva) = 11.43 + 7.62 A; 2,33 + 1.04 A; 2.07 + 1.10 A; 2) PMS (x 106 UFC/mg) = 0.099 + 0.095 A; 0.027 + 0.018 A; 0.007 + 0.003 A; 3) ASP (mg/mg) = 6.89 + 0.62 AC; 8.46 + 0.80 AB; 6.11 + 0.59 C; 4) ASF (mg/g) = 36.67 + 10.10 A; 48.12 + 19.23 A; 52.21 + 15.12 A; 5) T0 = 6.72 + 0.12 A; 6.88 + 0.13 A; 6.65 + 0.11 A; 6) T5 = 5.61 + 0.13 A; 5.71 + 0.13 A; 5.70 + 0.12 A; 7) DpH = 1.12 + 0.11 A; 1.17 + 0.11 A; 0.95 + 0.10 A. Means followed by the same letter do not differ significantly (P < 0.05). The data show that although the baking soda-containing dentifrice demonstrated, collectively, a trend to influence positively the various factors of dental caries, it did not differ significantly from SILICA and CARBONATE dentifrices.\",\"PeriodicalId\":77611,\"journal\":{\"name\":\"Revista de odontologia da Universidade de Sao Paulo\",\"volume\":\"13 1\",\"pages\":\"43-49\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista de odontologia da Universidade de Sao Paulo\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1590/S0103-06631999000100010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de odontologia da Universidade de Sao Paulo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/S0103-06631999000100010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Efeito de um dentifrício fluoretado contendo bicarbonato de sódio na contagem de estreptococos do grupo mutans, acidogenicidade e composição da placa dental
This investigation evaluated the effect of a fluoride baking soda-containing dentifrice on mutans streptococci counting, acidogenicity and composition of dental plaque. Twenty-three volunteers brushing their teeth 3 times a day, tested 3 formulations of fluoride (1500 ppm F), containing or sodium bicarbonate (12%) associated with calcium carbonate (CARB/BICAR), or calcium carbonate (CARBONATE), or silica (SILICA), in a double blind crossover trial, done in 3 phases of 30 days each. On the 28th day, 8-10 hours after the last brushing, a counting of mutans streptococci in saliva (SMS) was made. On the 30th day (after 48 hours during which the subjects were instructed to rinse with a slurry of toothpaste/water 3 times a day and sucrose 10% 6 times a day), the effect was analyzed in dental plaque, 10-12 hours after the last rinse: a) mutans streptococci (PMS); b) polysaccharide alkali-soluble (ASP); c) acid-soluble F (ASF) and d) pH in T0 (T0), 5 min. after cariogenic challenge (T5), calculating DpH (T0 - T5). The results (mean + SE) according to the treatments with dentifrices SILICA, CARBONATE and CARB/BICAR, were respectively: 1) SMS (x 106 UFC/mL saliva) = 11.43 + 7.62 A; 2,33 + 1.04 A; 2.07 + 1.10 A; 2) PMS (x 106 UFC/mg) = 0.099 + 0.095 A; 0.027 + 0.018 A; 0.007 + 0.003 A; 3) ASP (mg/mg) = 6.89 + 0.62 AC; 8.46 + 0.80 AB; 6.11 + 0.59 C; 4) ASF (mg/g) = 36.67 + 10.10 A; 48.12 + 19.23 A; 52.21 + 15.12 A; 5) T0 = 6.72 + 0.12 A; 6.88 + 0.13 A; 6.65 + 0.11 A; 6) T5 = 5.61 + 0.13 A; 5.71 + 0.13 A; 5.70 + 0.12 A; 7) DpH = 1.12 + 0.11 A; 1.17 + 0.11 A; 0.95 + 0.10 A. Means followed by the same letter do not differ significantly (P < 0.05). The data show that although the baking soda-containing dentifrice demonstrated, collectively, a trend to influence positively the various factors of dental caries, it did not differ significantly from SILICA and CARBONATE dentifrices.