IgA抗变形链球菌在有无龋齿儿童中的应用

S. C. Yazaki, Cristiane Yumi Koga-Ito, Antonio Olavo Cardosos Jorge, C. S. Unterkircher
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引用次数: 6

摘要

龋齿是一种慢性传染病,至少需要四个因素才能形成。作为一个易感宿主,一个致病菌群,一个高蔗糖的饮食和时间。本研究评估了变形链球菌与牙菌斑之间的关系;有无龋齿患儿的变形链球菌和IgA抗体。为了达到这一目的,我们采用Mitis Salivarius bacitracin agar (DIFCO)测定菌落形成单位(CFU/mL),简化口腔卫生指数(SOHI)测定菌斑,ELISA检测抗体。获得的结果没有显示变形链球菌的集落形成单位和IgA抗体之间的任何相关性。龋齿患儿菌斑指数与特异性IgA有显著相关性。
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IgA anti-Streptococcus mutans em crianças com e sem cárie dentária
Dental caries is a chronic infectious disease that needs at least four components to develop. As a susceptible host, a pathogenic microbiota, a high-sucrose diet and time. This work assess the relationships between Streptococcus mutans and dental plaque; Streptococcus mutans and IgA antibodies in children with and without caries experience. In order to achieve this goal we have used Mitis Salivarius bacitracin agar (DIFCO) to determine the colony forming units (CFU/mL), the simplified oral hygiene index (SOHI) for measuring bacterial plaque and ELISA for antibody detection. The results obtained have not shown any correlations between colony forming units of S. mutans and IgA antibodies. A significant correlation was found between bacterial plaque index and specific IgA in children with carious lesions.
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