调查伊拉姆市先天性畸形的患病率及其相关因素

K. Sayehmiri, M. Kaffashian, Elahe Ranaei
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引用次数: 0

摘要

简介:先天性畸形是新生儿致残和死亡的常见原因,其治疗对社会来说费用高昂。本研究旨在探讨先天性畸形的患病率及其原因。材料与方法:本研究为描述性分析研究,人群包括2011年伊拉姆市所有医院的新生儿。数据收集表中包括异常类型、出生状况、医疗和遗传病史等变量。数据分析采用SPSS软件进行卡方检验和Fisher精确检验。结果:460名新生儿中,5.4%(25例)死于出生,3.7%(16例)出生时有先天缺陷。43.8%的畸形婴儿有家族史。31.3%的畸形儿有遗传综合征,其父母为近亲婚姻。在中枢神经系统和心血管系统有缺陷的婴儿中,18.8%的人表现出类似的疾病比例。泌尿系统、头部和颈部的缺陷各占12.5%。结论:本研究表明,近亲婚姻可能是遗传综合征最常见的遗传原因。
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Investigating the prevalence of congenital anomalies and its associated factors in Ilam city
Introduction: Congenital anomalies are a common cause of disability and mortality in newborns and their treatments involves high costs for the society. This study aimed to investigate the prevalence of congenital anomalies and their causes. Materials and methods: This research was a descriptive-analytical study and the population included all the newborns in hospitals of the city of Ilam in 2011. Variables of abnormality type, birth status, and medical and genetic illness histories were included into the data collection forms. Data was analyzed through Chi-square tests and Fisher's exact test using SPSS software. Results: Of 460 neonates, 5.4 percent (25 cases) had died at birth and 3.7 percent (16 infants) were born with a birth defect. 43.8 percent of malformed babies had a family history. 31.3 % of the malformed babies had genetic syndromes, whose parents had consanguineous marriage. 18.8% of babies with defects in the central nervous system and cardiovascular system showed a similar percentage of disorder. The defect in the urinary system, head and neck each accounted for 12.5 percent. Conclusion: This study shows that consanguineous marriages can be the most common genetic cause of genetic syndromes.
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