绞股蓝乙醇提取物抗氧化活性的测定

Q4 Pharmacology, Toxicology and Pharmaceutics Iranian Journal of Pharmaceutical Sciences Pub Date : 2021-01-01 DOI:10.22034/IJPS.2021.522481.1779
Alfina Ansafovna Nizamova, E. Galiakhmetova, K. Mochalov, D. Bokov, Golrokh Farnam, N. Kudashkina
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引用次数: 2

摘要

活性自由基的炎症反应在许多重要情况下起着主要作用,如果它们不被中和并在体内持续存在,就会发生许多疾病。抗氧化剂是体内消除这些自由基的关键资源。几个世纪以来,草药被广泛用于治疗疾病。绞股蓝生长在欧洲和亚洲的许多不同地区,是一种富含抗氧化剂的适应性植物。在本研究中,采用肾上腺素自氧化和化学发光两种不同的方法评估绞股蓝提取物的抗氧化作用,这两种方法均在俄罗斯获得专利。结果表明,有机溶剂更适合提取这些抗氧化剂,乙醇提取物的提取率为70%。这项初步工作可能为未来研究俄罗斯种植的这种草药治疗炎症和其他具有这种病理的疾病的抗氧化作用打开了新的大门。
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The Determination of Antioxidant Activity of Ethanol Extracts of Gynostemma Pentaphyllum
Inflammatory reactions of active radicals play a primary role in many vital circumstances, and if they are not neutralized and persist in the body, many diseases will occur. Antioxidants are the very critical resources available in the body to eliminate these free radicals. Medicinal herbs have been used extensively in the treatment of diseases for centuries. Gynostemma Pentaphyllum is grown in many different locations of Europe and Asia is an adaptogenic plant that is rich in antioxidants. During this study, the antioxidant effects of Gynostemma Pentaphyllum extract are evaluated using two different methods of adrenaline autooxidation and Chemiluminescence, both patented in Russia. Our results show that the organic solvent is more suitable for the extraction of these antioxidants with the ratio of 70% ethanolic extract being yield in more extraction. This preliminary work might open a new door for future studies on the antioxidant effects of this herb grown in Russia for the treatment of inflammations and other diseases with such pathology.
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来源期刊
Iranian Journal of Pharmaceutical Sciences
Iranian Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.50
自引率
0.00%
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0
期刊介绍: Iranian Journal of Pharmaceutical Sciences (IJPS) is an open access, internationally peer-reviewed journal that seeks to publish research articles in different pharmaceutical sciences subdivisions: pharmacology and toxicology, nanotechnology, pharmaceutics, natural products, biotechnology, pharmaceutical chemistry, clinical pharmacy and other pharmacy related topics. Each issue of the journal contents 16 outstanding research articles in area of pharmaceutical sciences plus an editorial written by the IJPS editors on one of the most up to date advances topics in pharmacy. All articles published by IJPS would be permanently accessible online freely without any subscription charges. Authors of the published articles have granted the right to use and disseminate their article to third parties.
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