APP、CST3、ITM2B基因突变在诱导遗传性脑淀粉样血管病综合征中的作用

Archives of hematology and blood diseases Pub Date : 2019-01-01 DOI:10.22259/2639-3581.0201001

S. Asadi

{"title":"APP、CST3、ITM2B基因突变在诱导遗传性脑淀粉样血管病综合征中的作用","authors":"S. Asadi","doi":"10.22259/2639-3581.0201001","DOIUrl":null,"url":null,"abstract":"HCAA syndrome is a genetic disorder that can lead to gradual loss of intellectual function (mental decline), stroke, and other neurological problems in the middle of adulthood. The mutation in the APP gene, located in the long arm of chromosome 21 as 21q21.3, is the most common genetic cause of HCAA syndrome.","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Role of Genetics Mutations in Genes APP, CST3, ITM2B in Inducate Hereditary Cerebral Amyloid Angiopathy Syndrome\",\"authors\":\"S. Asadi\",\"doi\":\"10.22259/2639-3581.0201001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"HCAA syndrome is a genetic disorder that can lead to gradual loss of intellectual function (mental decline), stroke, and other neurological problems in the middle of adulthood. The mutation in the APP gene, located in the long arm of chromosome 21 as 21q21.3, is the most common genetic cause of HCAA syndrome.\",\"PeriodicalId\":93414,\"journal\":{\"name\":\"Archives of hematology and blood diseases\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of hematology and blood diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22259/2639-3581.0201001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of hematology and blood diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22259/2639-3581.0201001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

HCAA综合征是一种遗传性疾病，可导致智力功能逐渐丧失(智力下降)、中风和其他神经系统问题。位于21号染色体长臂21q21.3的APP基因突变是HCAA综合征最常见的遗传原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

The Role of Genetics Mutations in Genes APP, CST3, ITM2B in Inducate Hereditary Cerebral Amyloid Angiopathy Syndrome

HCAA syndrome is a genetic disorder that can lead to gradual loss of intellectual function (mental decline), stroke, and other neurological problems in the middle of adulthood. The mutation in the APP gene, located in the long arm of chromosome 21 as 21q21.3, is the most common genetic cause of HCAA syndrome.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Archives of hematology and blood diseases

自引率

0.00%

发文量