Pub Date : 2023-01-01DOI: 10.22259/2639-3581.0501001
Y. Uemura, Mitsuo Okada, Masayuki Ishida
{"title":"Simultaneous Onset of Thrombocytopenia and Hypereosinophilia With Sars-Cov-2 Vaccine","authors":"Y. Uemura, Mitsuo Okada, Masayuki Ishida","doi":"10.22259/2639-3581.0501001","DOIUrl":"https://doi.org/10.22259/2639-3581.0501001","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68287714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.22259/2639-3581.0401001
J. Jbireal, Rabia A. M. Yahya, A. Azab, S. Alzahani
{"title":"Effect of Coronavirus Infection on Haematological Parameters in Covid-19 Patients in the Sabratha Region Western Libya","authors":"J. Jbireal, Rabia A. M. Yahya, A. Azab, S. Alzahani","doi":"10.22259/2639-3581.0401001","DOIUrl":"https://doi.org/10.22259/2639-3581.0401001","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68288168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0302002
Laura E. Finn, Jessica Foy, Evan L. Dvorin
{"title":"Pulmonary Tuberculosis Reactivation and CNS Involvement Following Treatment of Myelofibrosis with Ruxolitinib: Case Report and Review of the Literature of Incidence in Myeloproliferative Neoplasms","authors":"Laura E. Finn, Jessica Foy, Evan L. Dvorin","doi":"10.22259/2639-3581.0302002","DOIUrl":"https://doi.org/10.22259/2639-3581.0302002","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68288116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0302003
Mangwana Sadhana, Pravin Kumar
{"title":"Screening of Anti-SARS-CoV-2 IgG and IgM Antibodies in Blood Donors: An Experience during Beginning of COVID-19 Pandemic","authors":"Mangwana Sadhana, Pravin Kumar","doi":"10.22259/2639-3581.0302003","DOIUrl":"https://doi.org/10.22259/2639-3581.0302003","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68288160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0301001
Robert Walchack, Zelia Bowman, S. Wen, N. Shah, Kelly G. Ross, Abraham S. Kanate, A. Cumpston
Introduction: There is insufficient evidence regarding the optimal chemotherapy regimen for treatment of relapsed or refractory acute myeloid leukemia (RR-AML). We retrospectively compared the outcomes and toxicities between salvage chemotherapy with etoposide plus mitoxantrone (EM) versus clofarabine-based regimens in patients with RR-AML. Materials and Methods: Consecutive patients with RR-AML who received > 1 cycle of EM or a clofarabinebased regimen between March 2003 and April 2017. Results: A total of 93 patients were included in the study. Sixty-nine patients received EM and 24 patients received clofarabine-based regimens. Baseline characteristics were matched, except for a higher rate of previous EM therapy and primary refractory disease in the clofarabine arm. The overall remission rate (complete remission plus complete remission with incomplete hematologic recovery) was 36.2% in the EM arm versus 29.2% in the clofarabine arm (p = 0.62). The 3-year event-free survival (EFS) and overall survival (OS) was 17.6% and 41% in the EM arm, compared to 4.6% (p = 0.18) and 5% (p < 0.001) in the clofarabine arm. Of those treated with EM, 36.2% could undergo subsequent allogeneic hematopoietic cell transplantation (allo-HCT) versus 12.5% of those in the clofarabine arm (p = 0.04). Grade 3 or higher non-hematologic toxicities occurred in 35 (50.7%) patients in the EM arm, compared to 18 (75%) patients with a clofarabine-based regimen (p = 0.04). This is the first comparison of these two salvage chemotherapy options. Unfortunately, the imbalance with more refractory and heavily pretreated patients in the clofarabine arm limits conclusions, and more studies are necessary to validate outcomes with these regimens.
{"title":"Comparison of Clofarabine-Based Regimens Versus Etoposide Plus Mitoxantrone as Salvage Chemotherapy for Patients with Relapsed or Refractory Acute Myeloid Leukemia","authors":"Robert Walchack, Zelia Bowman, S. Wen, N. Shah, Kelly G. Ross, Abraham S. Kanate, A. Cumpston","doi":"10.22259/2639-3581.0301001","DOIUrl":"https://doi.org/10.22259/2639-3581.0301001","url":null,"abstract":"Introduction: There is insufficient evidence regarding the optimal chemotherapy regimen for treatment of relapsed or refractory acute myeloid leukemia (RR-AML). We retrospectively compared the outcomes and toxicities between salvage chemotherapy with etoposide plus mitoxantrone (EM) versus clofarabine-based regimens in patients with RR-AML. Materials and Methods: Consecutive patients with RR-AML who received > 1 cycle of EM or a clofarabinebased regimen between March 2003 and April 2017. Results: A total of 93 patients were included in the study. Sixty-nine patients received EM and 24 patients received clofarabine-based regimens. Baseline characteristics were matched, except for a higher rate of previous EM therapy and primary refractory disease in the clofarabine arm. The overall remission rate (complete remission plus complete remission with incomplete hematologic recovery) was 36.2% in the EM arm versus 29.2% in the clofarabine arm (p = 0.62). The 3-year event-free survival (EFS) and overall survival (OS) was 17.6% and 41% in the EM arm, compared to 4.6% (p = 0.18) and 5% (p < 0.001) in the clofarabine arm. Of those treated with EM, 36.2% could undergo subsequent allogeneic hematopoietic cell transplantation (allo-HCT) versus 12.5% of those in the clofarabine arm (p = 0.04). Grade 3 or higher non-hematologic toxicities occurred in 35 (50.7%) patients in the EM arm, compared to 18 (75%) patients with a clofarabine-based regimen (p = 0.04). This is the first comparison of these two salvage chemotherapy options. Unfortunately, the imbalance with more refractory and heavily pretreated patients in the clofarabine arm limits conclusions, and more studies are necessary to validate outcomes with these regimens.","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68287961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0301004
J. Jbireal, A. Azab
{"title":"Prevalence of Iron Deficiency Anaemia among School Children in Sabratha, Western Libya","authors":"J. Jbireal, A. Azab","doi":"10.22259/2639-3581.0301004","DOIUrl":"https://doi.org/10.22259/2639-3581.0301004","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68288038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0302001
Azab Elsayed Azab, Jbireal Jm
{"title":"The Relationship between ABO Blood Groups, Rhesus Factor and Breast Cancer","authors":"Azab Elsayed Azab, Jbireal Jm","doi":"10.22259/2639-3581.0302001","DOIUrl":"https://doi.org/10.22259/2639-3581.0302001","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68288105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0301005
R. Balgir
{"title":"Prenatal, Neonatal and Pediatric Health Care and Reproductive Medicine in Relation to Hemoglobinopathies in Three Stratified Communities of Central India","authors":"R. Balgir","doi":"10.22259/2639-3581.0301005","DOIUrl":"https://doi.org/10.22259/2639-3581.0301005","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68288091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22259/2639-3581.0301002
Naruko Suzuki, J. Hiraga, Y. Takagi, M. Narita, Y. Kagami
{"title":"Safety and Efficacy of Forodesine for a Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified with Liver Failure","authors":"Naruko Suzuki, J. Hiraga, Y. Takagi, M. Narita, Y. Kagami","doi":"10.22259/2639-3581.0301002","DOIUrl":"https://doi.org/10.22259/2639-3581.0301002","url":null,"abstract":"","PeriodicalId":93414,"journal":{"name":"Archives of hematology and blood diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68287977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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