反安慰剂效应在临床试验中的影响

IF 1.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Open Access Journal of Clinical Trials Pub Date : 2012-11-05 DOI:10.2147/OAJCT.S33730
L. Colloca
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引用次数: 9

摘要

神经生物学和临床研究表明,学习机制和对益处的期望对大脑、精神和身体都有强大的影响,在日常临床实践中有可能缓解许多症状。扮演拮抗剂的角色是“反安慰剂效应”,这是由一个人的信仰、以前的经历和他或她的临床遭遇产生的负面预期产生的负面影响。对反安慰剂效应的研究表明,信息披露和传递信息的方式可能导致这些不利影响。在这篇文章中,我们回顾了与反安慰剂效应有关的神经生物学和医学研究,因为这些发现对甲基安非他明很重要
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The influence of the nocebo effect in clinical trials
Neurobiological and clinical studies have shown that learning mechanisms and expectations of benefits powerfully affect the brain, mind, and body, with the potential of reliev - ing many symptoms during the course of daily clinical practice. Playing the role of antagonist is the "nocebo effect," which results from negative expectations derived from one's beliefs, previous experiences, and his or her clinical encounters that produce negative effects. Research on the nocebo effect indicates that information disclosure and the manner in which information is delivered can contribute to these adverse effects. In this article, we review neurobiological and medical studies relating to the nocebo effect, as these findings are important for the meth -
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来源期刊
Open Access Journal of Clinical Trials
Open Access Journal of Clinical Trials MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
3.90
自引率
0.00%
发文量
2
审稿时长
16 weeks
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