反安慰剂效应在临床试验中的影响

IF 1.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Open Access Journal of Clinical Trials Pub Date : 2012-11-05 DOI:10.2147/OAJCT.S33730
L. Colloca
{"title":"反安慰剂效应在临床试验中的影响","authors":"L. Colloca","doi":"10.2147/OAJCT.S33730","DOIUrl":null,"url":null,"abstract":"Neurobiological and clinical studies have shown that learning mechanisms and expectations of benefits powerfully affect the brain, mind, and body, with the potential of reliev - ing many symptoms during the course of daily clinical practice. Playing the role of antagonist is the \"nocebo effect,\" which results from negative expectations derived from one's beliefs, previous experiences, and his or her clinical encounters that produce negative effects. Research on the nocebo effect indicates that information disclosure and the manner in which information is delivered can contribute to these adverse effects. In this article, we review neurobiological and medical studies relating to the nocebo effect, as these findings are important for the meth -","PeriodicalId":19500,"journal":{"name":"Open Access Journal of Clinical Trials","volume":"7 1","pages":"61-68"},"PeriodicalIF":1.4000,"publicationDate":"2012-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/OAJCT.S33730","citationCount":"9","resultStr":"{\"title\":\"The influence of the nocebo effect in clinical trials\",\"authors\":\"L. Colloca\",\"doi\":\"10.2147/OAJCT.S33730\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Neurobiological and clinical studies have shown that learning mechanisms and expectations of benefits powerfully affect the brain, mind, and body, with the potential of reliev - ing many symptoms during the course of daily clinical practice. Playing the role of antagonist is the \\\"nocebo effect,\\\" which results from negative expectations derived from one's beliefs, previous experiences, and his or her clinical encounters that produce negative effects. Research on the nocebo effect indicates that information disclosure and the manner in which information is delivered can contribute to these adverse effects. In this article, we review neurobiological and medical studies relating to the nocebo effect, as these findings are important for the meth -\",\"PeriodicalId\":19500,\"journal\":{\"name\":\"Open Access Journal of Clinical Trials\",\"volume\":\"7 1\",\"pages\":\"61-68\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2012-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2147/OAJCT.S33730\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Access Journal of Clinical Trials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/OAJCT.S33730\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Access Journal of Clinical Trials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/OAJCT.S33730","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 9

摘要

神经生物学和临床研究表明,学习机制和对益处的期望对大脑、精神和身体都有强大的影响,在日常临床实践中有可能缓解许多症状。扮演拮抗剂的角色是“反安慰剂效应”,这是由一个人的信仰、以前的经历和他或她的临床遭遇产生的负面预期产生的负面影响。对反安慰剂效应的研究表明,信息披露和传递信息的方式可能导致这些不利影响。在这篇文章中,我们回顾了与反安慰剂效应有关的神经生物学和医学研究,因为这些发现对甲基安非他明很重要
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The influence of the nocebo effect in clinical trials
Neurobiological and clinical studies have shown that learning mechanisms and expectations of benefits powerfully affect the brain, mind, and body, with the potential of reliev - ing many symptoms during the course of daily clinical practice. Playing the role of antagonist is the "nocebo effect," which results from negative expectations derived from one's beliefs, previous experiences, and his or her clinical encounters that produce negative effects. Research on the nocebo effect indicates that information disclosure and the manner in which information is delivered can contribute to these adverse effects. In this article, we review neurobiological and medical studies relating to the nocebo effect, as these findings are important for the meth -
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Open Access Journal of Clinical Trials
Open Access Journal of Clinical Trials MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
3.90
自引率
0.00%
发文量
2
审稿时长
16 weeks
期刊最新文献
A Multidomain Intervention Program for Older People with Dementia: A Pilot Study Randomized Clinical Trial Comparing Insulin Fast Dissolving Films versus Control Group for Anosmic Patients for Improving Their Health and Social Qualities of Life Treatment of Oropharyngeal Symptoms: A Prospective, Single-Dose, Placebo-Controlled, Randomized Clinical Trial Post-Trial Considerations for an Early Phase Optogenetic Trial in the Human Brain Reviewing Treatments for Cocaine Consume Problems: The Gabapentinoid Alternative
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1