{"title":"计算设计能否取代人类设计抗菌肽?","authors":"J. Cheng","doi":"10.23880/aii-16000110","DOIUrl":null,"url":null,"abstract":"Antimicrobial peptides (AMPs) are a class of naturally occurring peptides produced by organisms across multiple kingdoms to defend the host against the invading pathogen. AMPs offer great alternatives to develop the next generation antimicrobial agents. Today, there are 3140 naturally occurring and synthetic antimicrobial peptides identified from six kingdoms according to The Antimicrobial Peptide Database (APD) [1-3], presenting a good arsenal against microbial infection and providing a wide selection for antimicrobial drug development.","PeriodicalId":93259,"journal":{"name":"Annals of immunology & immunotherapy","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Can Computational Design Replace Human Design of Antimicrobial Peptides?\",\"authors\":\"J. Cheng\",\"doi\":\"10.23880/aii-16000110\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Antimicrobial peptides (AMPs) are a class of naturally occurring peptides produced by organisms across multiple kingdoms to defend the host against the invading pathogen. AMPs offer great alternatives to develop the next generation antimicrobial agents. Today, there are 3140 naturally occurring and synthetic antimicrobial peptides identified from six kingdoms according to The Antimicrobial Peptide Database (APD) [1-3], presenting a good arsenal against microbial infection and providing a wide selection for antimicrobial drug development.\",\"PeriodicalId\":93259,\"journal\":{\"name\":\"Annals of immunology & immunotherapy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of immunology & immunotherapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23880/aii-16000110\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of immunology & immunotherapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23880/aii-16000110","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Can Computational Design Replace Human Design of Antimicrobial Peptides?
Antimicrobial peptides (AMPs) are a class of naturally occurring peptides produced by organisms across multiple kingdoms to defend the host against the invading pathogen. AMPs offer great alternatives to develop the next generation antimicrobial agents. Today, there are 3140 naturally occurring and synthetic antimicrobial peptides identified from six kingdoms according to The Antimicrobial Peptide Database (APD) [1-3], presenting a good arsenal against microbial infection and providing a wide selection for antimicrobial drug development.