负重关节选择性关节置换术中增强恢复(快速通道)方案

A. M. Ageenko, D. S. Nikiforov, T. Nikiforova, M. Lebedeva
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引用次数: 0

摘要

目的:评价乳清蛋白加碳水化合物饮料对膝关节置换术后患者代谢参数、一般状态及恢复时间的影响。方法:对2021年3月至7月60例髋关节和膝关节骨关节炎(OA)患者的围手术期进行评估。所有患者均在脊髓麻醉下行髋关节或膝关节置换术。此外,研究组患者在手术前2小时接受ProvideXtra®饮料。除此之外,围手术期的患者管理是标准的。在手术当天或第二天达到身体健康、脊柱阻滞消除和血流动力学稳定后,对患者进行活动和直立。结果:治疗4小时后,两组患者血糖水平均升高,对照组为7.15±0.94 mmol/l比7.88±1.18 mmol/l,差异有统计学意义(p=0.02)。两组患者出院前血红蛋白水平分别为100±16 g/l和101±18 g/l,差异无统计学意义(p=0.86)。研究组出院前总蛋白水平差异为63.1±6.1 g/l vs 59.2±5.9 g/l (p=0.17)。研究组的垂直化时间如下:10例患者在手术当天垂直化,其余20例患者在手术第二天垂直化。在对照组中,8例患者在手术当天垂直放置,22例患者在第二天垂直放置。对照组2例术后恶心需纠正。结论:现代手术方法包括最大限度地保留自然喂养,基于术后增强恢复(ERAS®)的概念。然而,在手术当天选择特定饮食的指导方针仍有待最终确定。使用现成的碳水化合物-蛋白质混合物是一种方便的解决方案,可以提供所需的能量和蛋白质。因此,该混合物对术后蛋白质代谢的影响还有待进一步研究。关键词:加速康复,营养混合物,髋关节置换,膝关节置换。
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ENHANCED RECOVERY (FAST-TRACK) PROGRAM IN ELECTIVE ARTHROPLASTY OF WEIGHT-BEARING JOINTS
Objective: To evaluate the effect of feeding with a whey protein plus carbohydrate drink on metabolic parameters, general state of the patient and recovery time after knee and hip arthroplasty. Methods: The results of the perioperative period of 60 patients with osteoarthritis (OA) of the hip and knee were evaluated between March and July 2021. All patients underwent hip or knee arthroplasty under spinal anaesthesia. In addition, patients of the study group received the ProvideXtra® Drink 2 hours before surgery. Otherwise, the management of patients in the perioperative period was the standard. Mobilisation and verticalisation of patients were carried out after achieving physical fitness, resolution of the spinal block and haemodynamic stability on the day of surgery or the next day. Results: In all patients after 4 hours, increased glucose levels were recorded in both groups, statistically significant in the control group – 7.15±0.94 versus 7.88±1.18 mmol/l (p=0.02). The decrease in haemoglobin level had no difference in the study groups and before discharge was 100±16 g/l versus 101±18 g/l (p=0.86). The difference in total protein level before discharge was in favour of the study group, 63.1±6.1 versus 59.2±5.9 g/l (p=0.17). Verticalisation timing in the study group was as follows: 10 patients were verticalised on the day of surgery, and the remaining 20 patients – were on the next day. In the control group – 8 patients were verticalised on the day of surgery and 22 – on the next day. In the control group, 2 cases of postoperative nausea requiring correction were observed. Conclusion: The modern surgical approaches include the maximal preservation of natural feeding, based on the Enhanced Recovery after Surgery (ERAS®) concept. However, guidelines for choosing a particular diet on the day of surgery remain to be finally established. Using ready-made carbohydrate-protein mixtures is a convenient solution that delivers the required amount of energy and protein. Therefore, the effect of the mixture on protein metabolism in the postoperative period remains to be elucidated through further studies. Keywords: Accelerated rehabilitation, nutrient mixture, hip arthroplasty, knee arthroplasty.
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