大面积肺栓塞表现为梗阻性休克在尼日利亚妇女:一个病例报告

Bernard B Akpu, Chidimma A. Ahaneku, Agbo J Etim, Ezoke J Epoke, D. E. Elem, B. Ekeng, Edikan B Bassey, C. Njoku, V. Ansa, C. O. Odigwe
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引用次数: 0

摘要

背景:大面积肺栓塞是一种危及生命的紧急情况,如果及时诊断和紧急干预延迟,死亡率高,特别是在表现为阻塞性休克的患者中。它通常需要先进的治疗方法,如全身溶栓、药物机械导管指导治疗、手术栓塞切除和下腔静脉过滤器放置。熟练人力的缺乏、诊断的延误、纤溶药物的相对缺乏和高成本,特别是在资源贫乏的环境中,可能是这些患者临床结果不佳和最终死亡的原因。病例介绍:我们报告一名50岁的尼日利亚Bahumono族妇女,因突发呼吸困难而入院。在就诊时,她有呼吸急促、心动过速和低血压。d -二聚体和肌钙蛋白I水平升高。计算机断层肺血管造影(CTPA)与静脉造影剂证实诊断为大量肺栓塞。患者最初使用低分子肝素治疗,然后静脉使用阿替普酶溶栓,随后使用达比加群片出院。出院时症状已消失,病情稳定3个多月。结论:肺栓塞是静脉血栓栓塞中最严重的临床表现,当其表现为块状时可造成灾难性后果。及时诊断和紧急适当的医疗干预确保了良好的临床效果。
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Massive Pulmonary Embolism Presenting as Obstructive Shock in a Nigerian Woman: A Case Report
Background: Massive pulmonary embolism is a life-threatening emergency associated with high mortality if prompt diagnosis and urgent intervention is delayed, especially in patients presenting in obstructive shock. It usually requires advanced therapies such as systemic thrombolysis, pharmaco-mechanical catheter-directed therapy, surgical embolectomy and inferior vena cava filter placement. The dearth in skilled manpower, delay in diagnosis, relative unavailability and high cost of fibrinolytics especially in resource poor environments may account for poor clinical outcomes and eventually death in such patients. Case Presentation: We present a 50-year-old Nigerian woman of Bahumono ethnicity who was admitted into our hospital with complains of sudden onset breathlessness. On presentation, she was tachypneic, tachycardic and hypotensive. D-Dimer and Troponin I levels were elevated. Computed tomography pulmonary angiography (CTPA) with intravenous contrast confirmed the diagnosis of massive pulmonary embolism. She was initially treated with low molecular weight heparin, then thrombolyzed with intravenous alteplase and later discharged on tablet dabigatran. Her symptoms had resolved at the time of discharge and she has remained stable for over 3 months. Conclusion: Pulmonary embolism, the most serious clinical presentation of venous thromboembolism can become catastrophic when it presents as the massive type. Prompt diagnosis and urgent appropriate medical intervention ensures good clinical outcomes.
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