activegin®与可的松对PMA诱导的人细胞炎症的影响

Journal of orthopaedics and sports medicine Pub Date : 2022-01-01 DOI:10.26502/josm.511500069

F. Reichl, Fangfang Liu, Christof Hogg

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引用次数: 0

摘要

目的:研究activegin®与可的松对PMA诱导的人外周血单核细胞(PBMCs)的影响。方法:10名献血者外周血(1 × 10细胞/ml) (5 f, 5 m;45-55岁)在培养基中生长，在PMA存在或不存在的情况下暴露于activegin®或可的松。收集上清液，评估细胞因子/物质:IL-6、TNF-α、IL-8、IL-1 β和IL-10的浓度。测定活性氧(ROS)含量

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Effect of Actovegin® Versus Cortisone on PMA‐Induced Inflammation on Human Cells

Purpose: The effect of Actovegin® versus Cortisone was investigated on PMA induced human Peripheral Blood Mononuclear Cells (PBMCs). Methods: PBMCs (1 × 10 cells/ml) from ten blood donors (5 f, 5 m; 45–55 years) were grown in medium and exposed to Actovegin® or Cortisone in the presence or absence of PMA. Supernatants were collected to assess the concentration of cytokines/substances: IL-6, TNF-α, IL-8, IL-1 beta, and IL-10. The Reactive Oxygen Species (ROS) were assessed

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Journal of orthopaedics and sports medicine

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