新生儿出生体重、胎龄与脐带血血脂水平相关性的研究

Joshi Siddhartha J, Nidhi Rai Gupta, Heloise Stanley
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引用次数: 0

摘要

背景与目的:动脉粥样硬化病变是一种主要的心血管危险因素,其发生始于生命早期。如果可以在儿童期预测到心血管危险因素的过早发展,就可以通过采取适当的措施有效地预防心血管事件。本研究的目的是了解脐带血血脂水平及其与新生儿出生体重和胎龄的关系。方法:本研究于2019年12月至2020年6月在德里曼戈尔普里桑杰甘地纪念医院儿科进行。在这项观察性横断面研究中,105名胎龄在28 ~ 0.05之间的新生儿。结论:低出生体重儿、早产儿和小胎龄儿的脂质水平明显高。因此,低出生体重儿、小于胎龄儿和早产儿应密切监测脂质相关疾病和合并症。
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Study of Cord Blood Lipid Levels and Its Correlation with Newborn’s Birth Weight and Gestational Age
, Abstract Background and objectives: The genesis of atherosclerotic lesions which is a major cardiovascular risk factor starts in the early life. If the premature development of cardiovascular risk factors can be anticipated during childhood, cardiovascular events can be prevented effectively by taking appropriate measures. The aim of the present study was to know cord blood lipid levels and its correlation with newborn’s birth weight and gestational age. Methods: Present study was conducted in the department of paediatrics, Sanjay Gandhi Memorial Hospital, Mangolpuri, Delhi, from December 2019 to June 2020. In this observational cross sectional study, 105 newborn babies whose gestational age was between 28 to <42 weeks were included with due consideration of inclusion and exclusion criteria as per study protocol. Results: Cord blood lipid levels were significantly high (P <0.05) in low birth weight babies. Cord high density lipoprotein with gender (p>0.05). Conclusions: Lipid levels were significantly high in low birth weight babies, preterm babies and small for gestational age babies. Hence, low birth weight babies, small for gestational age babies and preterm babies should be closely monitored for lipid related disorders and co-morbidities.
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