卵巢储备检测中抗苗勒管激素与窦卵泡计数的相关性

A. K, Partha Majumder S, S. R
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引用次数: 1

摘要

背景:卵巢储备决定了女性的生殖能力以及她所拥有的卵母细胞的数量和质量。这是一种复杂的临床状态,与年龄、遗传和环境因素有关。它可以反映女性的内分泌功能和生育能力,随着年龄的增长而逐渐下降。方法:本研究是一项横断面研究,在萨瓦尔伊纳姆医学院医院和萨瓦尔当地一家私立医院的妇产科门诊进行。该研究于2019年7月至2019年12月期间进行。本研究的样本量为120人。结果:年龄在35 ~ 40岁之间者44例,占36.7%。BMI平均值±SD为26.61±1.96,不孕持续时间(年)为3.75±1.64,卵巢总体积(ml)为7.66±1.32。输卵管因素27例(21.7%),其次为男性因素24例(20%),PCOS 20例(16.7%),子宫内膜异位症6例(5%),不明原因不孕22例(18.3%)。低组AFC(平均±SD)为07.15±4.82,其中AMH(平均±SD)为6.66±5.34,正常组次之,分别为09.38±3.59和9.48±3.91,高组分别为15.45±5.46和16.08±5.23。两项预测指标无显著相关。结论:AMH是卵巢储备检测最可靠的指标。血清AMH水平与相对较低的窦腔卵泡计数有很强的相关性。卵巢储备试验条件差的患者可进行腔内卵泡计数。
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Correlation of Anti Mullerian Hormone and Antral Follicular Count in Ovarian Reserve Testing
Background: Ovarian reserve defines a woman’s reproductive ability and the number and quality of oocytes she possesses. It is a complex clinical state dependent on age, genetics, and environmental issues. It can reflect women’s endocrine function and fertility which may gradually decrease with increasing age. Methods: This study was a cross-sectional study conducted at the out-patient department of Obstetrics and Gynae, in Enam Medical College Hospital, Savar and a local private hospital at Savar. The study was conducted during the period of July 2019-December 2019. The sample size for this study was 120. Result: The most respondent 44 (36.7%) were in between 35-40 years. The mean ± SD of BMI was 26.61 ± 1.96 and followed by duration of infertility (years) was 3.75 ± 1.64, total ovarian volume (ml) was 7.66 ± 1.32. Tubal factor was found in 27 (21.7%) cases and followed by male factor was in 24 (20%), PCOS was in 20 (16.7%), endometriosis was in 6 (5%), unexplained infertility was in 22 (18.3%). In low group AFC (mean ± SD) was 07.15 ± 4.82 where AMH (mean ± SD) was 6.66 ± 5.34 and followed by normal was 09.38 ± 3.59 and 9.48 ± 3.91and high was 15.45 ± 5.46 and 16.08 ± 5.23. There was no significance correlation found in these two predictors. Conclusion: AMH is considered as most reliable investigation for ovarian reserve testing. Serum AMH level has strong correlation with comparatively low cost Antral follicular count. Antral follicular count can be done in poor patients for ovarian reserve test.
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