年龄对艾滋病毒感染者心血管、运动和生活方式的影响

Martín G. Rosario, Elizabeth Orozco
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引用次数: 2

摘要

背景:艾滋病毒感染者经历各种与衰老相关的合并症。随着这一人群年龄的增长,这些合并症会导致身体损伤,降低功能自主性和生活质量。目的:本研究旨在描述影响西班牙裔拉丁裔艾滋病毒感染者(PLHIV)年龄的各种因素。方法:从波多黎各La Perla de Gran Precio艾滋病社区中心登记的323名参与者的记录中提取数据。参与者被分为以下年龄组进行比较:40岁以下(L-HIV组)和40岁以上(U-HIV组)。采用多重单因素方差分析(Multiple one-way anova)比较两个年龄组之间的数据,基于五个组成部分:心脏、运动、脂质面板、合并症和生活方式。结果:L-HIV组44人(年龄=35.4+/-3.7),U-HIV组279人(年龄=56.3+/-7.4)。有氧运动成分(在次最大跑步机测试上完成的时间和峰值心率)在年龄较大的年龄组中明显更少。在次最大跑步机测试中,U-HIV组也表现出明显较慢的步态速度和较低的倾斜度。最后,U-HIV组由更多患有多种合并症的参与者组成。结论:在西班牙裔拉丁裔PLHIV中,U-HIV组除了多重发病率增加外,还发现了更显著的心血管和运动缺陷。未来的调查需要解决的是,诊断后的时间是否是一个可接受的指标,心脏运动恶化和多重合并症在这一人群中经历的高潮。
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The Influence of Age on Cardiovascular, Motor, and Lifestyle Components in Hispanic-Latinos Living with HIV
Background: People living with HIV experience various comorbidities associated with aging. As this population grows older, these comorbidities cause physical impairments that decrease functional autonomy and quality of life. Purpose: This investigation aims to characterize various components affecting Hispanic Latino people living with HIV (PLHIV) concerning age. Methods: Data was extracted from 323 participants’ records enrolled in La Perla de Gran Precio’s HIV Community Center in Puerto Rico. Participants were allocated into the following age groups for comparison: 40 years or less (L-HIV group) and above 40 years of age (U-HIV group). Multiple one-way ANOVAs were applied to compare the data between the two age groups based on five components: cardio, motor, lipid panel, comorbidities, and lifestyle. Results: There were 44 participants allocated to the L-HIV group (age =35.4+/-3.7) and 279 to the U-HIV group (age=56.3+/-7.4). The cardio components (time completed on the submaximal treadmill test and peak heart rate) were significantly less in the upper age group. The U-HIV group also demonstrated substantially slower gait speed and less inclination achieved on the submaximal treadmill test. Lastly, the U-HIV group consisted of more participants with multiple comorbidities. Conclusion: In Hispanic Latino PLHIV, more significant cardiovascular and motor deficits were identified in the U-HIV group in addition to an increased rate of multi-morbidity. Future inquiries are desired to resolve if the time since diagnosis is an acceptable indicator of cardio-motor deterioration and an upsurge in multiple comorbidities experienced in this population.
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