疗养条件下COVID-19长期综合征患者的免疫学治疗

IF 0.3 Q4 REHABILITATION Acta Balneologica Pub Date : 2023-01-01 DOI:10.36740/abal202302102
I. Ponikowska, P. Adamczyk, R. Wojciechowski, Krzysztof Jarosz
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引用次数: 1

摘要

目的:本研究的目的是评价疗养条件下治疗长冠综合征患者的有效性。材料与方法:33例符合研究条件的患者。他们都是经聚合酶链反应(PCR)检测确诊的病毒感染患者,符合“长冠综合征”标准。这些患者感染急性期的病程各不相同:22%有轻度症状,60%有中度症状,18%有重度症状。患者采用我们自己的治疗方案,包括:饮食治疗、运动疗法、按摩疗法、物理疗法和氧气疗法。每位患者每天接受5个单独选择的治疗程序,持续14至28天。每天监测体温、饱和度、血压、体重及一般临床情况。治疗前后采用循环劳力计间接负荷试验进行体能临床评估,根据Astrand-Ryhming标准图确定一般体能水平和最大吸氧能力(VO2max/l/min)。结果:临床情况有统计学意义的改善。10例患者(占全部研究患者的1/3)所有症状均缓解,其余患者症状减轻。治疗前后平均值差异有统计学意义。在物理能力方面,确定了由能力水平决定的总体改进。46%的研究患者最初的体能水平较低或非常低,治疗后没有出现体能低的症状。这些患者达到了平均体能水平。治疗前后VO2max平均值的差异无统计学意义,这可能是由于能够使用循环测功仪进行压力测试的患者较少。结论:1/在疗养条件下治疗长冠综合征患者是非常有效和有益的,为多发病患者提供了综合治疗。2/制定适当的治疗方案不仅可以提高患者的生活质量,还可以提高患者的非特异性免疫力,调节肠道微生物群,并可能有助于预防未来的感染。
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BALNEOLOGICAL TREATMENT OF PATIENTS WITH LONG COVID-19 SYNDROME IN HEALTH-RESORT CONDITIONS
Aim: The aim of our research was to evaluate the effectiveness of treating patients with Long COVID Syndrome in health-resort conditions. Materials and Methods: 33 patients were qualified for the research. They have all suffered virus infection confirmed by PCR test and met the criteria of Long COVID Syndrome. Course of the acute phase of infection varied among these patients: 22% had mild, 60% moderate and 18% severe symptoms. Patients were treated with our own program including: dietary treatment, kinesiotherapy, balneotherapy, physical therapy and Oxygen therapy. Each patient underwent 5 individually selected therapeutic procedures per day for the period of 14 to 28 days. Each day body temperature, saturation, blood pressure, weight and general clinical condition were monitored. Before and after treatment there was a clinical assessment of physical capacity based on indirect stress test on cycle ergometer, determining general physical capacity level and the maximum capacity of Oxygen absorption (VO2max/l/min.) according to Astrand-Ryhming normogram. Results: statistically significant improvement in clinical condition has been achieved. In case of 10 patients (1/3 of all researched) all syndromes resolved, other patients’ symptoms became fewer and less severe. Differences between average values before and after treatment were statistically significant. In terms of physical capacity a general improvement determined by capacity level was ascertained. 46% of patients researched had initially low or very low capacity level, and after treatment none of them presented the symptoms of low physical capacity. Those patients reached the average physical capacity level. Differences between the average values of VO2max before and after treatment were not statistically significant, which is probably due to little number of patients capable of taking the stress test with the use of cycle ergometer. Conclusions: 1/ Treating patients with Long COVID Syndrome in health-resort conditions is very effective and beneficial, and provides comprehensive therapy of patients with multi-morbidity. 2/ Properly prepared program of treating Long COVID Syndrome allows not only to improve patients’ life quality, but also increases their non-specific immunity, regulates gut microbiome and may help in preventing future infections.
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Acta Balneologica
Acta Balneologica REHABILITATION-
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66.70%
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