SARS-CoV-2:基因组、新变异和免疫个体感染风险

Edy Parwanto
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引用次数: 0

摘要

新冠肺炎疫情是由SARS-CoV-2引起的。这种局势令人担忧,因为它造成了不确定性,并已成为一个世界问题。关于新冠肺炎疫情,已经开展了SARS-CoV-2基因组分析。SARS-CoV-2基因组包含29.903个核苷酸(nt)。SARS-CoV-2基因组由:5′UTR、ORF 1ab基因、S基因、ORF 3a基因、E基因、M基因、ORF 6基因、ORF 7a基因、ORF 7b基因、ORF 8基因、N基因、ORF 10基因和3′UTR组成。据报道发现了B.1.1.7 (20I/501Y.V1)、B.1.351 (20H/501Y.V2)、B.1.429 (452R.V1)、p .1系(20J/501Y.V3)等新变种。因此,上述新变体SARS-CoV-2的存在会影响免疫个体的感染风险。
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SARS-CoV-2: Genome, New Variant and Risk of Infection in Immunized Individuals
The COVID-19 outbreak was caused by SARS-CoV-2. This situation is concerning because it has created uncertainty and has become a world problem. Regarding the COVID-19 outbreak, a genomic analysis of SARS-CoV-2 has been carried out. The genome of SARS-CoV-2 contains 29.903 nucleotides (nt). The SARS-CoV-2 genome consists of the: 5’ UTR, ORF 1ab gene, S gene, ORF 3a gene, E gene, M gene, ORF 6 gene, ORF 7a gene, ORF 7b gene, ORF 8 gene, N gene, ORF 10 gene and 3’ UTR. It has been reported about the discovery of a new variant namely B.1.1.7 (20I/501Y.V1), B.1.351 (20H/501Y.V2), B.1.429 (452R.V1), P.1-lineage (20J/501Y.V3). Consequently, the presence of the new variant of SARS-CoV-2 described above affects the risk of infection in immunized individuals.
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