增强型可注射水凝胶的自愈特性

IF 1.4 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY AIMS Materials Science Pub Date : 2023-01-01 DOI:10.3934/matersci.2023016
Connor Castro, Zachary R. Brown, E. Brewer
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引用次数: 0

摘要

与其他类型的植入物相比,可注射聚合物提供了很大的好处;然而,他们往往会遭受更多的机械磨损,可能需要更换种植体来恢复这些机械性能。本实验的目的是研究一种可注射水凝胶的自我修复能力,以增强其对先前成型植入物的自我修复能力。这是通过进行拉伸强度测试来检查随着时间的增加机械性能的潜在下降,以及染料渗透测试来检查水凝胶愈合区域之间界面键的形成来完成的。在两次注射之间有几个时间点,从两次注射之间的0分钟一直到两次注射之间的48小时。试验显示,与拉伸试验的单次注射相比,增加的注射次数没有统计学差异。然而,我们的结果显示,自愈关节的机械断裂增加,线性回归测试显示,随着注射间隔时间的增加,染料扩散速率降低。结果表明,水凝胶具有较强的自愈能力,且随着注射间隔时间的增加,其力学性能会缓慢下降。基于此,该测试可应用于其他可注射植入物和磨损植入物的无创解决方案,并显示出可能独特且有益的自我修复特性的科学依据。
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Self-healing properties of augmented injectable hydrogels over time
Injectable polymers offer great benefits compared to other types of implants; however, they tend to suffer from increased mechanical wear and may need a replacement implant to restore these mechanical properties. The purpose of this experiment is to investigate an injectable hydrogel's self-healing ability to augment itself to a previously molded implant. This was accomplished by performing a tensile strength test to examine potential diminishing mechanical properties with increasing time, as well as dye penetration tests to examine the formation of interfacial bonds between healed areas of hydrogels. There were several time points in between injections that were explored, from 0 min between injections all the way up to 48 h in between injections. The tests showed no statistical differences of the increased injection times compared to the single injection for the tensile test. However, our results showed an increase of mechanical breaks at self-healed joints, as well as a linear regression test showed a decrease in dye diffusion rate as time between injections increase. These results show that the hydrogel has strong self-healing abilities, and as time between injections increase, they mechanical properties will slowly decrease. Based on this, the tests can be applied to other injectable implants and a noninvasive solution to a worn-down implant, as well as show scientific backing to a possibly unique and beneficial self-healing property.
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来源期刊
AIMS Materials Science
AIMS Materials Science MATERIALS SCIENCE, MULTIDISCIPLINARY-
CiteScore
3.60
自引率
0.00%
发文量
33
审稿时长
4 weeks
期刊介绍: AIMS Materials Science welcomes, but not limited to, the papers from the following topics: · Biological materials · Ceramics · Composite materials · Magnetic materials · Medical implant materials · New properties of materials · Nanoscience and nanotechnology · Polymers · Thin films.
期刊最新文献
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