免疫与营养在衰老中的相互作用——事实与争议

Q3 Medicine Nutrition and Healthy Aging Pub Date : 2019-01-01 DOI:10.3233/NHA-170034

I. Alam, A. Almajwal, Wajid Alam, Ibrar Alam, N. Ullah, Mahmoud Abulmeaaty, S. Razak, Saleem Khan, G. Pawelec, P. Paracha

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引用次数: 13

摘要

营养以多种方式影响免疫，不同的营养物质会影响许多免疫参数。衰老也会影响免疫力，使营养、年龄和免疫力之间相互作用的结果复杂起来。此外，一种营养素的缺乏可能会影响另一种营养素的正常代谢，从而引起继发性营养不良的连锁反应，从而改变整个免疫系统。在这篇文章中，我们回顾了这些相互作用和可能的机制调解这种关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The immune-nutrition interplay in aging – facts and controversies

Nutrition influences immunity in multiple ways, with different nutrients affecting many immune parameters. Aging also affects immunity, making the outcome of the interplay between nutrition, age and immunity complex. Moreover, a particular nutrient may alter the whole immune constellation as deficiency of one nutrient may affect the proper metabolism of another nutrient and elicit a chain reaction of secondary malnutrition. In this article, we review these interactions and the possible mechanisms mediating such relationships.

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来源期刊

Nutrition and Healthy Aging Agricultural and Biological Sciences-Food Science

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： Nutrition and Healthy Aging is an international forum for research on nutrition as a means of promoting healthy aging. It is particularly concerned with the impact of nutritional interventions on the metabolic and molecular mechanisms which modulate aging and age-associated diseases, including both biological responses on the part of the organism itself and its micro biome. Results emanating from both model organisms and clinical trials will be considered. With regards to the latter, the journal will be rigorous in only accepting for publication well controlled, randomized human intervention trials that conform broadly with the current EFSA and US FDA guidelines for nutritional clinical studies. The journal will publish research articles, short communications, critical reviews and conference summaries, whilst open peer commentaries will be welcomed.