Senile hypopituitarism:characteristics of diagnosis and treatment

Hypopituitarism is a clinical syndrome caused by reduced production of adenohypophyseal hormones.Senile hypopituitarism may show a much more complicated picture of clinical manifestations,and a delay in diagnosis and treatment may lead to rapid development of pituitary crisis.Therefore,clinicians should be alerted for senile hypopituitarism.For patients with hyponatremia,hypoglycemia and unexplained coma,an evaluation of pituitary function should be performed.Patients with confirmed hypopituitarism should remain on regular hormone replacement therapy(HRT) and are absolutely not allowed for self-initiated tapering or discontinuation of medications.