泊松广义Birnbaum-Saunders治疗模型及其在乳腺癌数据中的应用

Mojtaba Meshkat, A. Baghestani, F. Zayeri
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引用次数: 1

摘要

治愈率生存模型通常用于模拟长期幸存者的终生数据。我们假设引起感兴趣事件的竞争原因的数目符合泊松分布,而发生感兴趣事件的时间符合广义Birnbaum-Saunders分布。本文给出了泊松GB-S分布的定义,并给出了其密度函数的有用表示,从而便于获得一些数学性质。用极大似然法估计了具有固形率的模型参数。针对不同的样本量和审查百分比,进行了多次模拟,并对来自医学领域的真实数据集进行了分析。
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The Poisson Generalized Birnbaum-Saunders Cure Model and Application in Breast Cancer Data
The cure rate survival models are generally used to model lifetime data with long term survivors. We assumes the number of competing causes of the event of interest has the Poisson distribution and the time to the event of interest follows the Generalized Birnbaum-Saunders distribution. The Poisson GB-S distribution has been defined and useful representations for its density function have been presented which facilitates obtaining some mathematical properties. The parameters of the model with cure rate have been estimated using the maximum likelihood method. For different sample sizes and censoring percentages, several simulations have been performed and a real data set from the medical area has been analyzed.
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