埃塞俄比亚西北部两所区级医院药物处方模式评价

Muluken Wubetu, Dagninet Derebe, T. Mulaw, T. Yimer, Getachew Hailu
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引用次数: 12

摘要

背景:根据世界卫生组织的数据,超过一半的药物处方和配药不当,因此有一半的患者服用不当。为了降低发病率和死亡率及其不良后果,适当使用药物具有巨大的影响。方法:本研究旨在评估菲诺特塞拉姆和莫塔地区医院门诊药房的药物处方模式。本研究采用横断面回顾性方法,选取菲诺特·塞拉姆和莫塔地区医院门诊药房。2015年3月1日至2016年2月29日共纳入处方纸362份。采用世界卫生组织采用的结构化标准化形式,通过观察患者的处方文件来填写数据。数据输入EPI INFO 7.0版本,然后使用世界卫生组织药物使用指标进行分析。结果:回顾性分析1年处方362张。每次就诊的平均处方药物数为2.1,范围为1至5。使用抗生素或注射剂就诊的比例分别为58.8%和3.6%,使用通用名和基本药物清单的比例分别为98.4% (n=742)和81% (n=611)。阿莫西林(9.2%)、环丙沙星(6.2%)和强力霉素(4.8%)是常见的抗生素处方。结论:我们的研究表明,大多数抗生素的处方模式偏离了世界卫生组织的建议。一些抗生素的过度使用也需要紧急干预。该研究还显示,使用通用名称开处方的做法越来越多。我们的研究揭示了一个非常有趣的观点,即在被研究的医院中,诸如多药房和基本药物清单处方等问题并没有受到关注。研究人员和政策制定者可以利用本研究收集的基线数据来改进这两家医院的处方实践。最后,这两家医院的药物处方做法与世界卫生组织的要求相差不远。
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Assessment of Drug Prescription Pattern in Two District Hospitals, Northwest Ethiopia
Background: According to World Health Organization more than half of all medicines are prescribed and dispensed improperly, hence half of patients take them inappropriately. To reduce morbidity and mortality and their adverse outcomes, appropriate drug utilization has an enormous impact. Methodology: This study is aimed to assess prescription patterns of drugs in Finote Selam and Motta District Hospital in outpatient pharmacy unit. The study was cross-sectional retrospective by selecting the outpatient pharmacy units of Finote Selam and Motta district hospitals. A total of 362 prescription papers were incorporated from March 01/2015 to February 29/2016. A structured standardized proforma, adopted from the world health organizations, was used to fill data by observing the prescriptions papers of patients. The data was entered into EPI INFO version 7.0, and then analyzed using World Health Organization drug use indicators. Results: A total of 362 prescriptions were reviewed retrospectively from a total of those prescribed for 1-year period. The average number of drugs prescribed per encounter was 2.1 with a range between 1 and 5. The percentage of encounters in which an antibiotic or injection was ordered was 58.8% and 3.6%, respectively while the percentage of those drugs prescribed by generic name and from an essential drug list was 98.4% (n=742) and 81% (n=611), respectively. Amoxicillin (9.2%), ciprofloxacin (6.2%), and doxycycline (4.8%) were among the common antibiotics prescribed. Conclusion: Our study showed that the prescription pattern for most antibiotics deviates from the one advised by the world health organization. There is also overuse of some antibiotics which needs urgent intervention. The study also revealed the occurrence of an increasing practice of prescribing drugs using generic names. The very interesting point that our study revealed is problems like poly pharmacy and prescribing from the essential drug list were not concerns in the studied hospitals. Baseline data gathered by this study can be used by researchers and policymakers to improve prescribing practice at these two Hospitals. Lastly, drug prescribing practices in these two hospitals are not far from the world health organization requirements.
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