{"title":"地理位置对黑草籽提取物多酚含量及其抗炎、抗氧化作用的影响比较研究","authors":"Singhal Rini, Verma Shweta, Singh Vijender, Bajaj Sakshi","doi":"10.56042/ijnpr.v14i1.1132","DOIUrl":null,"url":null,"abstract":"The herb Nigella sativa belonging to the family Ranunculaceae is a well-investigated plant that has a wide range of pharmacological effects. The study aimed to evaluate and compare the antioxidant and anti-inflammatory potential as well as phytochemical screening in terms of total phenolic and flavonoid content of N. sativa seeds collected from various locations in India to establish the impact of geographical location on phytoconstituents of the seeds. The total phenolic and flavonoid content in methanolic extracts were evaluated using the Folin-ciocalteu reagent and AlCl 3 colourimetric method respectively. The antioxidant activities of the extracts were evaluated using the DPPH method, while the anti-inflammatory activity of the extracts was determined in vitro using the bovine serum albumin denaturation assay. The extract of the seed from Vizag had the highest concentration of polyphenols, followed by those from Madhya Pradesh and Punjab. The study confirmed variations in the quantity of the phytoconstituents of N. sativa seeds of different geographical origins and their consequential impact on the antioxidant and anti-inflammatory activity indicating that the geographical location exerts a vital effect on the same.","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of geographical location on the polyphenolic content of Nigella sativa seed extract and the relative anti-inflammatory and antioxidant potential thereof: A comparative study\",\"authors\":\"Singhal Rini, Verma Shweta, Singh Vijender, Bajaj Sakshi\",\"doi\":\"10.56042/ijnpr.v14i1.1132\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The herb Nigella sativa belonging to the family Ranunculaceae is a well-investigated plant that has a wide range of pharmacological effects. The study aimed to evaluate and compare the antioxidant and anti-inflammatory potential as well as phytochemical screening in terms of total phenolic and flavonoid content of N. sativa seeds collected from various locations in India to establish the impact of geographical location on phytoconstituents of the seeds. The total phenolic and flavonoid content in methanolic extracts were evaluated using the Folin-ciocalteu reagent and AlCl 3 colourimetric method respectively. The antioxidant activities of the extracts were evaluated using the DPPH method, while the anti-inflammatory activity of the extracts was determined in vitro using the bovine serum albumin denaturation assay. The extract of the seed from Vizag had the highest concentration of polyphenols, followed by those from Madhya Pradesh and Punjab. The study confirmed variations in the quantity of the phytoconstituents of N. sativa seeds of different geographical origins and their consequential impact on the antioxidant and anti-inflammatory activity indicating that the geographical location exerts a vital effect on the same.\",\"PeriodicalId\":13297,\"journal\":{\"name\":\"Indian Journal of Natural Products and Resources\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Natural Products and Resources\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.56042/ijnpr.v14i1.1132\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Natural Products and Resources","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56042/ijnpr.v14i1.1132","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
Impact of geographical location on the polyphenolic content of Nigella sativa seed extract and the relative anti-inflammatory and antioxidant potential thereof: A comparative study
The herb Nigella sativa belonging to the family Ranunculaceae is a well-investigated plant that has a wide range of pharmacological effects. The study aimed to evaluate and compare the antioxidant and anti-inflammatory potential as well as phytochemical screening in terms of total phenolic and flavonoid content of N. sativa seeds collected from various locations in India to establish the impact of geographical location on phytoconstituents of the seeds. The total phenolic and flavonoid content in methanolic extracts were evaluated using the Folin-ciocalteu reagent and AlCl 3 colourimetric method respectively. The antioxidant activities of the extracts were evaluated using the DPPH method, while the anti-inflammatory activity of the extracts was determined in vitro using the bovine serum albumin denaturation assay. The extract of the seed from Vizag had the highest concentration of polyphenols, followed by those from Madhya Pradesh and Punjab. The study confirmed variations in the quantity of the phytoconstituents of N. sativa seeds of different geographical origins and their consequential impact on the antioxidant and anti-inflammatory activity indicating that the geographical location exerts a vital effect on the same.
期刊介绍:
Indian Journal of Natural Products and Resources (IJNPR), a quarterly journal, is dedicated to the exploration of topics that confront both educators, frontline workers in the fields, entrepreneurs and ultimate users of the value added products and their resources pertaining to both plants and animals. It publishes original research papers, reviews and short communications. The scope of the journal is multidisciplinary especially of applied nature. Papers on plant cultivation, fishery, apiary, poultry, dairy, disease and pest control measures, postharvest technology/practices, value added products and utilization of plants and animals in broader sense (including ethnobotany and pharmacology) are considered for publication.