分子内醛醇反应立体选择性合成顺式取代-3′-苯胺-2′,3′-二氢-4-2′-苯并[b]呋喃基香豆素

L. Shastri, S. Shastri, M. Kulkarni, V. Gupta, S. Goswami
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引用次数: 2

摘要

本研究报道了4-溴甲基香豆素与水杨基苯胺在丙酮中与两等量的碳酸钾反应,在室温下通过分子内醛化反应生成标题化合物。所制得的化合物热力学和动力学稳定,具有高度的立体选择性和优良的产率。
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Stereoselective Synthesis of cis-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[b]furanylcoumarins via Intramolecular Aldol Reactions
The present study reports the reaction of 4-bromomethylcoumarins with salicylidineaniline in acetone with two equivalents of potassium carbonate resulted in the formation of title compounds at room temperature via intramolecular aldolization. The obtained compound is thermodynamically and kinetically stable with highly stereoselective and excellent yield.
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来源期刊
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