应对COVID-19大流行期间神经退行性疾病的多学科方法

Q3 Biochemistry, Genetics and Molecular Biology Journal of Advanced Biotechnology and Experimental Therapeutics Pub Date : 2022-01-01 DOI:10.5455/jabet.2022.d100
Hannan, R. Dash, B. Timalsina, Y. A. Munni, Sarmistha Mitra, D. F. Oktaviani, Haque, A. Sohag, M. D. N. Meinita, I. Moon
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引用次数: 0

摘要

神经退行性疾病,包括阿尔茨海默病和帕金森病,是老年人痴呆症的主要原因。在未来的日子里,随着预期寿命的延长,预计痴呆症患者将出现惊人的增长。这种情况不仅发生在发达国家,也发生在发展中国家,那里的老年人生活在脆弱的环境中。即使在COVID-19(冠状病毒病-19)大流行中,情况也有所恶化。由于传统治疗策略的局限性,有必要探索包括药理学和非药物干预的综合方法。由于现有抗痴呆药物对患者存在诸多不良反应,应采用天然药物进行药物干预,探索靶向治疗。此外,非药物干预,如认知和运动康复,职业治疗和心理治疗需要探索。从这个角度来看,需要采用多学科方法,以便为管理这些具有巨大社会负担的新出现的健康问题制定一种可持续的病人友好治疗战略。©2022,孟加拉国微生物学、免疫学和先进生物技术学会。版权所有。
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Multidisciplinary approaches to coping with neurodegenerative disorders amid COVID-19 pandemic
Neurodegenerative disorders, including Alzheimer’s and Parkinson’s, are the leading causes of dementia in the elderly. In the coming days, an alarming upsurge of dementia patients is expected with increasing life expectancy. This is the scenario not only in the developed world but also in the developing world, where older people live in vulnerable situations. Even in the COVID-19 (coronavirus disease-19) pandemic, the situation has worsened. Due to the limitations of conventional therapeutic strategies, it is necessary to explore integrated approaches consisting of both pharmacological and non-pharmaceutical interventions. As existing anti-dementia drugs pose many adverse effects on patients, pharmacological intervention through naturally occurring agents should be employed to explore targeted therapy. Alongside, non-pharmacological interventions such as cognitive and motor rehabilitation, occupational therapy, and psychological therapy need to be explored. From this perspective, multidisciplinary approaches need to be employed in order to develop a sustainable patient-friendly treatment strategy for the management of these emerging health issues with tremendous social burdens. © 2022, Bangladesh Society for Microbiology, Immunology and Advanced Biotechnology. All rights reserved.
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来源期刊
Journal of Advanced Biotechnology and Experimental Therapeutics
Journal of Advanced Biotechnology and Experimental Therapeutics Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
CiteScore
1.90
自引率
0.00%
发文量
41
审稿时长
8 weeks
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