羟基磷灰石掺杂等离子体喷雾剂植入生物材料的效果

IF 2.9 Q2 ELECTROCHEMISTRY Journal of Electrochemical Science and Engineering Pub Date : 2023-01-01 DOI:10.5599/jese.1614
Amrinder Mehta, Gurbhej Singh
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引用次数: 13

摘要

羟基磷灰石(HAp)由于其良好的生物相容性,至今仍是骨科金属植入物中最常用的生物活性涂层之一。羟基磷灰石在金属植入物中的应用可以通过多种工艺来实现。等离子喷涂(PS)涂层因其可靠性,可负担性和保护金属表面免受生锈和磨损的能力而脱颖而出。由于材料的不利机械特性,如脆性、缺乏断裂韧性和拉伸强度不足,HAp在医学中的应用受到限制。此外,hap覆盖种植体的重塑持续时间明显更长,骨整合率明显较低,并且这些种植体不存在抗菌作用或特征。高分子材料的力学和生物学性能已经通过各种方法得到了改善,这些方法都属于表面改性策略的范畴。掺杂剂是一种非常成功地改变其特性的方法在HAp中使用掺杂剂就是其中一种方法。因此,本综述旨在巩固等离子体喷涂方法在种植体Hap涂层方面的研究数据,并评估该方法的优点和存在的问题。此外,本文还讨论了如何改变HAp的结构、化学和机械特征来帮助克服这些限制。总之,它解释了进入HAp结构的结合如何改变特征,当使用等离子喷涂方法涂覆时,改变植入物的功能。
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Consequences of hydroxyapatite doping using plasma spray to implant biomaterials
Hydroxyapatite (HAp) is still one of the most common bioactive coatings used on metal implants in orthopaedics due to its biocompatibility. The application of HAp to metallic implants can be accomplished using a variety of processes. Plasma spray (PS) coating stands out as the method of choice due to its dependability, affordability, and ability to protect metal surfaces against rust and wear. The use of HAp in medicine has been limited due to the material's unfavorable mechanical characteristics, such as brittleness, a lack of fracture toughness, and inadequate tensile strength. In addition, the remodeling durations of HAp-covered implants are significantly longer, the rate of osseointegration is significantly lower, and no antimicrobial actions or features are present in these implants. The mechanical and biological properties of HAp have been improved by applying various approaches, all of which fall under the category of surface modification tactics. Dopants are one of those strategies that are extremely successful at changing the characteristics and using them in HAp is one of those methods. As a result, this review study aims to consolidate data on implant Hap coating using the plasma spray approach and assess the benefits and problems associated with employing this method. In addition, the paper addresses how altering the structural, chemical, and mechanical features of HAp can assist in overcoming these limitations. In conclusion, it explains how the incorporation of entering the HAp structure can change the features that, when coated using the plasma spraying approach, alter the functionality of the implant.
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来源期刊
CiteScore
3.60
自引率
27.30%
发文量
90
审稿时长
6 weeks
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