Adenosquamous cell carcinoma of the stomach - Report of three cases

In the past ten years, 790 cases of gastric carcinoma were histologicallyproven in Taipei Municipal Jen-Ai Hospital, with only three cases of adenosquamous cell carcinoma(0.4%), including two females and one male. All these tumors meeting the strict criteria were bulky and ulcerative. The tumor was located at the antrum, cardia, and in the body of the residual stomach respectively. The patients' age, symptoms, endoscopic and roentgenographic findings did not differ from those of other types of gastric cancer in general. The pathogenesis of this neoplasm is reviewed and discussed. Two patients died of disease soon after surgery. The other was alive and followed in outpatient department eight months after surgery. The prognosis seemed poor because of extensive metastases to the liver, lymph nodes and other organs.