A Case of Prolactin-Producing Pituitary Adenoma with Pituitary Apoplexy during Third Trimester Pregnancy in which underwent an Emergency Surgery

The frequency of concomitant pituitary tumors during pregnancy is rare. We report the case of patient with prolactin (cid:514) producing pituitary adenoma with pituitary apoplexy during third trimester pregnancy who underwent an emergency surgery. A 21 (cid:514) year (cid:514) old woman was diagnosed with prolactin (cid:514) producing pituitary adenoma 3 years ago. After cabergoline （ CAB ） treatment was started, she became pregnant 2 years later and discontinued the CAB. Afterward, she developed bitemporal hemianopsia. Her serum PRL level was 647.0 ng / m(cid:9520). Her MRI revealed a sellar / presellar tumor that showed fluid (cid:514) fluid level, and the optic chiasma was compressed upward. She underwent transsphenoidal surgery after cesarean section. Histopathological examination of the tumor revealed a sparsely granulated lactotroph adenoma （ SGLA ） with aggressive findings. Her visual field defect was alleviated after surgery. SGLA accounts for the majority of prolactin (cid:514) producing pituitary adenomas. Patients with SGLA usually follow a benign course. Physiological changes due to pregnancy and discontinuation of CAB can affect the development of pituitary apoplexy and aggressive findings. In such cases, integrative treatment involving the cooperation between clinical departments is necessary.