智能血管化3D/4D/5D/6D打印组织支架。

IF 31.6 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Nano-Micro Letters Pub Date : 2023-10-31 DOI:10.1007/s40820-023-01187-2

Xiaoyu Han, Qimanguli Saiding, Xiaolu Cai, Yi Xiao, Peng Wang, Zhengwei Cai, Xuan Gong, Weiming Gong, Xingcai Zhang, Wenguo Cui

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引用次数: 0

摘要

血管对输送营养和氧气以及清除废物至关重要。具有功能性血管网络的支架修复材料在骨组织工程中有着广泛的应用。增材制造是一种通过将物质层层堆叠来制造三维固体的制造技术，主要包括但不限于3D打印，也包括4D打印、5D打印和6D打印。通过精确调整智能血管支架的机械结构和生物性能，它可以与血管化有效结合，以满足血管化组织支架的需求。在此，根据血管化对组织的重要性，系统地讨论了从新生血管到血管化对骨组织工程的发展。此外，重点介绍了血管化3D打印支架材料的研究进展和未来前景，分为四类：功能性血管化3D打印机构架、基于细胞的血管化3D相机构架、负载特定载体的血管化三维相机构架和仿生血管化3D机构架。最后，简要回顾了血管组织工程、心血管系统、骨骼肌、软组织等相关组织中的血管化增材制造组织支架，并讨论了在智能血管化组织再生方面取得重大进展的挑战和发展努力。

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Intelligent Vascularized 3D/4D/5D/6D-Printed Tissue Scaffolds

Highlights

Comprehensive and systematic discussion of vascularized additive manufacturing scaffolds for bone tissue repair is provided.
The development mechanism of blood vessels and the relationship between bone tissue engineering and blood vessels are discussed.
Vascularized additively manufactured scaffolds in tissue repair are discussed in terms of issues, opportunities, and challenges.
Intelligent vascularized 3D/4D/5D/6D-printed tissue scaffolds are discussed.

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来源期刊

Nano-Micro Letters NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

42.40

自引率

4.90%

发文量

715

审稿时长

13 weeks

期刊介绍： Nano-Micro Letters is a peer-reviewed, international, interdisciplinary and open-access journal that focus on science, experiments, engineering, technologies and applications of nano- or microscale structure and system in physics, chemistry, biology, material science, pharmacy and their expanding interfaces with at least one dimension ranging from a few sub-nanometers to a few hundreds of micrometers. Especially, emphasize the bottom-up approach in the length scale from nano to micro since the key for nanotechnology to reach industrial applications is to assemble, to modify, and to control nanostructure in micro scale. The aim is to provide a publishing platform crossing the boundaries, from nano to micro, and from science to technologies.