Hassan Karimi-Maleh, Afsaneh L Sanati, Rozhin Darabi
{"title":"生物医学、药物输送和药物分析中的纳米材料。","authors":"Hassan Karimi-Maleh, Afsaneh L Sanati, Rozhin Darabi","doi":"10.5599/admet.2125","DOIUrl":null,"url":null,"abstract":"After the introduction of nanotechnology as a new science, there were tremendous changes in its application. Nanomaterials rapidly penetrate a diverse area of biomedicine and pharmaceutical research, including drug development, drug delivery, tissue engineering and medicinal chemistry. Its versatile use helps in alleviating complex difficulties faced with drug administration and absorption, controlled release, targeted delivery and cellular uptake. Due to their distinctive physico-chemical properties and ability to form various solid-state formulations, they find increased use in the preparation of new drug formulations, imaging techniques and particularly in medicinal chemistry as catalysts for the sensitive determination of drugs and other biologically active compounds. The role of nanomaterials as catalysts in the preparation of substances with pharmacological properties, the preparation of sensors, or the degradation and removal of medicinal compounds polluting the environment is undeniable.","PeriodicalId":7259,"journal":{"name":"ADMET and DMPK","volume":"11 4","pages":"433-434"},"PeriodicalIF":3.4000,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626511/pdf/","citationCount":"0","resultStr":"{\"title\":\"Nanomaterials in biomedicine, drug delivery and pharmaceutical analysis.\",\"authors\":\"Hassan Karimi-Maleh, Afsaneh L Sanati, Rozhin Darabi\",\"doi\":\"10.5599/admet.2125\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"After the introduction of nanotechnology as a new science, there were tremendous changes in its application. Nanomaterials rapidly penetrate a diverse area of biomedicine and pharmaceutical research, including drug development, drug delivery, tissue engineering and medicinal chemistry. Its versatile use helps in alleviating complex difficulties faced with drug administration and absorption, controlled release, targeted delivery and cellular uptake. Due to their distinctive physico-chemical properties and ability to form various solid-state formulations, they find increased use in the preparation of new drug formulations, imaging techniques and particularly in medicinal chemistry as catalysts for the sensitive determination of drugs and other biologically active compounds. The role of nanomaterials as catalysts in the preparation of substances with pharmacological properties, the preparation of sensors, or the degradation and removal of medicinal compounds polluting the environment is undeniable.\",\"PeriodicalId\":7259,\"journal\":{\"name\":\"ADMET and DMPK\",\"volume\":\"11 4\",\"pages\":\"433-434\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2023-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626511/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ADMET and DMPK\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5599/admet.2125\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ADMET and DMPK","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5599/admet.2125","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Nanomaterials in biomedicine, drug delivery and pharmaceutical analysis.
After the introduction of nanotechnology as a new science, there were tremendous changes in its application. Nanomaterials rapidly penetrate a diverse area of biomedicine and pharmaceutical research, including drug development, drug delivery, tissue engineering and medicinal chemistry. Its versatile use helps in alleviating complex difficulties faced with drug administration and absorption, controlled release, targeted delivery and cellular uptake. Due to their distinctive physico-chemical properties and ability to form various solid-state formulations, they find increased use in the preparation of new drug formulations, imaging techniques and particularly in medicinal chemistry as catalysts for the sensitive determination of drugs and other biologically active compounds. The role of nanomaterials as catalysts in the preparation of substances with pharmacological properties, the preparation of sensors, or the degradation and removal of medicinal compounds polluting the environment is undeniable.
期刊介绍:
ADMET and DMPK is an open access journal devoted to the rapid dissemination of new and original scientific results in all areas of absorption, distribution, metabolism, excretion, toxicology and pharmacokinetics of drugs. ADMET and DMPK publishes the following types of contributions: - Original research papers - Feature articles - Review articles - Short communications and Notes - Letters to Editors - Book reviews The scope of the Journal involves, but is not limited to, the following areas: - physico-chemical properties of drugs and methods of their determination - drug permeabilities - drug absorption - drug-drug, drug-protein, drug-membrane and drug-DNA interactions - chemical stability and degradations of drugs - instrumental methods in ADMET - drug metablic processes - routes of administration and excretion of drug - pharmacokinetic/pharmacodynamic study - quantitative structure activity/property relationship - ADME/PK modelling - Toxicology screening - Transporter identification and study