S. V. Toshchakov, E. V. Grosfeld, A. D. Kozlova, A. S. Krylova, M. V. Patrushev
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Prospects for Using Metagenomic Analysis As a Tool for The Accurate Diagnosis of Capripoxvirus Infections in Farm Animals
Infectious diseases of small domestic ruminants caused by viruses belonging to the Capripoxvirus genus are a serious economic threat. However, the diagnostic tools currently available for these pathogens do not provide sufficient strain information for effective disease control. This can be solved by sequencing and analysis of the full virus genome, which is currently achievable by the use of next generation sequencing technologies followed by metagenomic analysis. This review discusses the biology of Capripoxvirus pathogens, and the diagnostic and disease control tools in the context of introducing metagenomic analysis as the primary tool for pathogen identification.
期刊介绍：
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.
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