目标人口数据的更新和基因地理学混合模块的测试

IF 0.5 Q4 GENETICS & HEREDITY Forensic Science International: Genetics Supplement Series Pub Date : 2022-12-01 DOI:10.1016/j.fsigss.2022.09.006

H.S. Mogensen , T. Tvedebrink , V. Pereira , P.S. Eriksen , N. Morling

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引用次数: 1

摘要

来自斯洛文尼亚、希腊、阿尔巴尼亚和厄立特里亚的个体通过Precision ID Ancestry Panel进行了分类，并被纳入GenoGeographer的九个参考人群（撒哈拉以南非洲、非洲之角、北非、中东、欧洲、南亚/中亚、东亚以及格陵兰岛东部和西部）。我们测试了GenoGeographer与外加剂模块在3548名假设属于参考群体的个体的AIM图谱上的性能。共有3387个（95.5%）剖面被分配给一个或多个参考种群，无论是单个种群还是两个或多种群的混合物，而161个（4.5%）剖面没有被分配给任何参考种群或其混合物。在GenoGeographer中没有参考来源人群的1486份AIM图谱中，来自北美和南美的AIM图谱的排斥率超过70%，而来自中亚、北亚和东北亚的AIM谱的排斥率低于20%。

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Update of aims population data and test with the genogeographer admixture module

Individuals from Slovenia, Greece, Albania, and Eritrea were typed with the Precision ID Ancestry Panel and included among GenoGeographer’s nine reference populations (Sub-Saharan Africa, Horn of Africa, North Africa, Middle East, Europe, South/Central Asia, East Asia, and East and West Greenland). We tested the performance of GenoGeographer with the Admixture Module on AIM profiles of 3548 individuals assumed to belong to one of the reference populations. A total of 3387 (95.5 %) profiles were assigned to one or more of the reference populations, either a single population or an admixture of two or more populations, while 161 (4.5 %) profiles were not assigned to any reference population or admixtures thereof. For 1486 AIM profiles with no reference population of origin in GenoGeographer, the rejection rate was more than 70 % for AIM profiles from North and South America and less than 20 % for those from Central, North, and Northeast Asia.

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来源期刊

Forensic Science International: Genetics Supplement Series Medicine-Pathology and Forensic Medicine

CiteScore

0.40

自引率

0.00%

发文量

122

审稿时长

25 days

期刊介绍： The Journal of Forensic Science International Genetics Supplement Series is the perfect publication vehicle for the proceedings of a scientific symposium, commissioned thematic issues, or for disseminating a selection of invited articles. The Forensic Science International Genetics Supplement Series is part of a duo of publications on forensic genetics, published by Elsevier on behalf of the International Society for Forensic Genetics.