评估厄瓜多尔法医STR标记的种群结构

R. Flores-Espinoza , A.N. Angulo-Pozo , A. Garzón-Salazar , A. Cabrera-Andrade , E. Paz-Cruz , G. Burgos , L. Gusmão
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引用次数: 1

摘要

欧洲人、美洲原住民和非洲人之间持续的混合事件在整个厄瓜多尔领土上发生得不同,形成了多样化的基因组成。因此,为了评估全国15个STR的遗传多样性划分情况,分析了842个混合种群样本。我们还评估了在使用国家数据库估计LRs时对人口结构进行调整的效果。结果表明,为了准确评估法医证据,可以通过对人口结构进行适当调整来证明使用国家数据库的合理性。
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Evaluating population structure of Ecuador for forensic STR markers

The continuous admixture events among Europeans, Native Americans, and Africans occurred differently throughout the Ecuadorian territory, creating a diversified genetic composition. Therefore, to evaluate how the genetic diversity is partitioned along the country for 15 STRs, 842 admixed-population samples were analyzed. We also evaluated the effect of applying an adjustment for population structure when estimating LRs using a national database. The results showed that to accurately assess forensic evidence, the use of a national database may be justified with the application of an appropriate adjustment for population structure.

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来源期刊
Forensic Science International: Genetics Supplement Series
Forensic Science International: Genetics Supplement Series Medicine-Pathology and Forensic Medicine
CiteScore
0.40
自引率
0.00%
发文量
122
审稿时长
25 days
期刊介绍: The Journal of Forensic Science International Genetics Supplement Series is the perfect publication vehicle for the proceedings of a scientific symposium, commissioned thematic issues, or for disseminating a selection of invited articles. The Forensic Science International Genetics Supplement Series is part of a duo of publications on forensic genetics, published by Elsevier on behalf of the International Society for Forensic Genetics.
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