怀孕期间未完成睡眠呼吸暂停测试的决定因素

K. Antony, A. L. Rice, Sakshi Bajaj, Abigail M. Wiedmer, N. Jacobson, Julia Nick, Allison Eichmann, A. K. Stanic, M. Bazalakova
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摘要

对阻塞性睡眠呼吸暂停(OSA)筛查呈阳性的孕妇,在妊娠期间完成检测对于OSA的诊断和治疗是必不可少的,因为后者可以降低妊娠期发生高血压疾病的风险。为了确定潜在的障碍,我们评估了未完成睡眠呼吸暂停测试的预测因素,这些预测因素是在怀孕期间通过筛查确定为OSA高危人群的。我们假设未完成睡眠呼吸暂停测试可以通过保险状况和产科因素(如测试时的胎龄)来预测。方法:我们对睡眠妊娠数据库中的前500人进行回顾性分析,其中包括OSA筛查阳性的孕妇和孕前患者;排除经筛选的先入为主者。使用多变量泊松回归来确定哪些因素与未完成独立相关。结果445例患者中,214例(48.1%)完成了睡眠呼吸暂停测试。在单变量分析中,与未完成检测相关的因素包括妊娠晚期转诊、较高胎次、一个或多个活产儿、早产史、先兆子痫史、2型糖尿病、无伴侣状态、种族和付款人。大声打鼾或目睹呼吸暂停的症状与睡眠呼吸暂停测试完成的发生率增加有关。多变量泊松回归表明,拥有公共保险可以预测怀孕期间未完成睡眠呼吸暂停测试。结论:在这项小型研究中,公共保险是孕期未完成睡眠呼吸暂停测试的独立预测因子。这些发现有助于提高患者在怀孕期间完成睡眠呼吸暂停测试的能力。
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Determinants of non-completion of sleep apnea testing during pregnancy
Study objectives Completion of testing during pregnancy for those who screen positive for obstructive sleep apnea (OSA) is imperative for the diagnosis and treatment of OSA, as the latter may reduce the risk of developing hypertensive disorders of pregnancy. To identify potential barriers, we assessed predictors of non-completion of sleep apnea testing by people identified to be at high risk of OSA by screening during pregnancy. We hypothesized that non-completion of sleep apnea testing would be predicted by insurance status and obstetric factors, such as gestational age at time of testing. Methods We performed a retrospective analysis of the first 500 people in our sleep pregnancy database which includes both pregnant and preconception patients who screened positive for OSA; those screened preconception were excluded. Multivariable Poisson regression was used to determine which factors were independently associated with non-completion. Results Of 445 referred, 214 (48.1%) completed sleep apnea testing. Factors associated with non-completion of testing on univariate analysis included referral in the third trimester, higher parity, one or more living children, history of preterm birth, history of preeclampsia, type 2 diabetes mellitus, non-partnered status, race, and payor. Symptoms of loud snoring or witnessed apneas were associated with increased incidence of sleep apnea testing completion. Multivariable Poisson regression demonstrated that having public insurance predicted non-completion of sleep apnea testing during pregnancy. Conclusion In this small study, public insurance was an independent predictor of non-completion of sleep apnea testing during pregnancy. These findings aid efforts to improve patient completion of sleep apnea testing during pregnancy.
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