AHI系统对阻塞性睡眠呼吸暂停严重程度分级的缺陷

IF 1 Q4 CLINICAL NEUROLOGY Sleep Science Pub Date : 2021-06-19 DOI:10.5935/1984-0063.20220001
Rashmi Soori, Nandakishore Baikunje, I. D’sa, N. Bhushan, B. Nagabhushana, G. Hosmane
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引用次数: 6

摘要

阻塞性睡眠呼吸暂停(OSA)是许多非传染性疾病(NCD)的主要潜在合并症,肥胖是一种常见的风险因素。阻塞性睡眠呼吸暂停的发病率和患病率自30年前出现以来一直在不断上升。在糖尿病、高血压、内分泌紊乱和血管疾病等主要非传染性疾病中,精准治疗潜在的OSA至关重要。根据呼吸暂停低通气指数(AHI)将OSA分为轻度、中度和重度。根据严重程度分级,OSA的治疗范围从改变生活方式到口腔器械、持续气道正压通气(CPAP)和手术。AHI重度分级系统在OSA中存在一些固有的缺陷,将AHI重度分级系统作为“圣杯”可能会适得其反。AHI系统将呼吸暂停和呼吸不足等同为相同的事件,而生理效应差异很大。AHI系统不考虑呼吸暂停的持续时间或呼吸暂停事件时的体位。我们详细讨论了AHI系统对OSA严重程度分级的缺陷。
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Pitfalls of AHI system of severity grading in obstructive sleep apnoea
Obstructive sleep apnoea (OSA) is the major underlying co-morbidity in many of the non-communicable diseases (NCD) due to obesity as a common risk factor. Incidence and prevalence of OSA is on the constant rise ever since this entity came to forefront three decades ago. Precise treatment of underlying OSA is extremely important in major NCDs like diabetes mellitus, hypertension, endocrine disorders and vascular diseases. OSA is subcategorized in to mild, moderate and severe based of apnoea-hypopnea index (AHI). Based on the severity grading, treatment of OSA ranges from life style modifications to oral appliances, continuous positive airway pressure (CPAP) and surgeries. AHI system of severity grading in OSA has several inherent shortcomings and using AHI system for severity grading as the holy grail is likely to be counter-productive. AHI system equates apnoea and hypopnea as equal events, whereas physiological effects vary significantly. AHI system does not account duration of apnoea or body position during apnoeic events. We discuss at length the pitfalls of AHI system of severity grading in OSA.
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来源期刊
Sleep Science
Sleep Science CLINICAL NEUROLOGY-
CiteScore
2.50
自引率
12.50%
发文量
124
审稿时长
10 weeks
期刊最新文献
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