脊索重建与切除小叶修复退行性二尖瓣后小叶脱垂。

Y. Chua, P. Y. Pang, Y. P. Yap, Zakir-Hussain Abdul Salam, Yang Tian Chen
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Outcomes at 6 years: freedom from severe mitral regurgitation (group R 97.1% ± 2.0%, group C 100%, P = 0.288), freedom from moderate or severe mitral regurgitation (group R 97.1% ± 2.0%, group C 94.4% ± 5.4%, P = 0.541). Group C patients received larger annuloplasty rings and had significantly lower postoperative transmitral gradients. CONCLUSIONS Leaflet resection and chordal reconstruction are effective techniques for repair of degenerative posterior mitral leaflet prolapse. Both techniques result in a low incidence of recurrent mitral regurgitation. 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引用次数: 8

摘要

目的总结退行性二尖瓣后小叶脱垂的二尖瓣修复经验,比较二尖瓣脊索重建与小叶切除的效果。方法2000 - 2014年,205例患者行退行性二尖瓣后小叶脱垂成功修复术。144例(51.5%)行小叶切除(R组),98例(48.5%)行脊索重建(C组)。随访率为96.5%,平均随访6.1±4.0年。结果患者平均年龄57.0±11.0岁。男性占73.8%。环成形术195例(96.5%)。30天内无手术死亡。7年总生存率为97.8%±1.3%。6年时:无严重二尖瓣反流(R组97.1%±2.0%,C组100%,P = 0.288),无中度或重度二尖瓣反流(R组97.1%±2.0%,C组94.4%±5.4%,P = 0.541)。C组患者接受较大的环成形术,术后透射梯度明显降低。结论小叶切除加脊索重建是修复退行性二尖瓣后小叶脱垂的有效方法。两种方法均可降低二尖瓣返流的发生率。索索重建适应较大的环成形术环,并与较低的透射梯度相关。
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Chordal Reconstruction versus Leaflet Resection for Repair of Degenerative Posterior Mitral Leaflet Prolapse.
OBJECTIVE To review our experience of mitral valve repair for degenerative posterior mitral leaflet prolapse, comparing the outcomes of chordal reconstruction and leaflet resection. METHODS From 2000 to 2014, 205 patients underwent successful repair for degenerative posterior mitral leaflet prolapse. One hundred and four (51.5%) underwent leaflet resection (group R) and 98 (48.5%) underwent chordal reconstruction (group C). Follow-up was 96.5% complete with a mean follow-up of 6.1 ± 4.0 years. RESULTS Mean age was 57.0 ± 11.0 years. Males accounted for 73.8%. Ring annuloplasty was performed in 195 (96.5%). There were no operative mortalities within 30 days. Overall survival was 97.8% ± 1.3% at 7 years. Outcomes at 6 years: freedom from severe mitral regurgitation (group R 97.1% ± 2.0%, group C 100%, P = 0.288), freedom from moderate or severe mitral regurgitation (group R 97.1% ± 2.0%, group C 94.4% ± 5.4%, P = 0.541). Group C patients received larger annuloplasty rings and had significantly lower postoperative transmitral gradients. CONCLUSIONS Leaflet resection and chordal reconstruction are effective techniques for repair of degenerative posterior mitral leaflet prolapse. Both techniques result in a low incidence of recurrent mitral regurgitation. Chordal reconstruction accommodates larger annuloplasty rings and is associated with lower transmitral gradients.
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