一撮盐不会杀死:盐片在逆转不完全四肢瘫痪患者顽固性直立性低血压中的作用

Muhamad Faizal Zainudin, Alicia Dixie Abraham, Mohd Razali Hasim, Nurul Diyanah Zenian
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摘要

背景和目的:直立性低血压是脊髓损伤的一种已知并发症,特别是在四肢瘫痪和胸部截瘫患者中。它是由病人倾斜直立引起的,通常通过去除沉淀因素很容易逆转。盐片是一种古老的医疗补充剂,通过保留水分来扩大血容量。我们提出一个顽固性直立性低血压在不完全四肢瘫痪,解决后,开始服用盐片。方法:患者是一名58岁的男性,患有背景性高血压,在积极的颈部按摩后出现颈部疼痛,并伴有进行性肢体无力,持续6天。他在报告前一天出现尿潴留和肠潴留。紧急MRI扫描显示颈椎钝性损伤伴颈脊髓挫伤,硬膜外血肿,椎前软组织挫伤,从C4到C6脊柱水平。他接受了保守的类固醇治疗。在康复病房,患者在倾斜台运动时出现多次晕厥发作。持续的因素是抗高血压药物,贫血和尿路感染,导致多尿和电解质失衡。尽管优化了液体摄入,治疗了潜在的医学问题,消除了诱因,并采取了腹部绑扎和弹力袜等额外措施,但直立性低血压仍然存在。结果:服用TDS盐片1 g后,晕厥发作逐渐缓解。患者耐受倾斜台运动直至抬高90°,随后进展为长时间坐在轮椅上。患者出院时完全没有晕厥,只需极少的辅助即可完成站立到轮椅的转移。结论:直立性低血压是阻碍脊髓损伤康复进展的可治疗障碍。因此,对于难治性病例,应考虑采用简单、廉价和容易获得的治疗方案,如盐片。
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A Pinch of Salt Won’t Kill: The Role of Salt Tablets in Reversing Intractable Orthostatic Hypotension in an Incomplete Tetraplegic Patient
Background and aim: Orthostatic hypotension is a known complication of spinal cord injury, especially in individuals with tetraplegia and thoracic paraplegia. It is triggered by tilting the patient upright and often easily reversed by removing the precipitating factors. The salt tablet is an old medical supplement that works as a blood volume expander by retaining water. We present a case of intractable orthostatic hypotension in incomplete tetraplegia, which resolved after the initiation of salt tablets. Methods: The patient was a 58-year-old gentleman with background hypertension who presented with neck pain following an aggressive neck massage, associated with progressive limb weakness, for six days duration. He developed urinary and bowel retention one day before the presentation. Urgent MRI scan revealed blunt injury at cervical spine with contusion of the cervical spinal cord, epidural haematoma, and contusion of prevertebral soft tissue from C4 till C6 spinal level. He was treated conservatively with steroids. In the rehabilitation ward, the patient developed multiple syncopal episodes during tilt table exercises. The perpetuating factors were antihypertensive medications, anaemia, and urinary tract infection, which resulted in polyuria and electrolyte imbalances. The orthostatic hypotension persisted, despite optimising fluid intake, treating underlying medical issues, removing triggers, and adopting additional measures such as abdominal binder and elastic stockings. Results: Following the initiation of salt tablets 1 gram TDS, the syncopal attacks gradually resolved. The patient tolerated the tilt table exercises until 90° elevation and subsequently progressed into sitting in the wheelchair for an extended period. The patient was completely free of syncope at discharge and required minimal assistance to perform stand transfer to the wheelchair. Conclusion: Orthostatic hypotension is a treatable barrier to progress in spinal cord injury rehabilitation. Therefore, simple, cheap, and easily accessible treatment options such as salt tablets should be considered in intractable cases.
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