{"title":"Epophen物质在常压缺氧中的作用研究","authors":"K. Ostrenko, A. Ovcharova, O. P. Yegorova","doi":"10.33647/2074-5982-19-2-45-53","DOIUrl":null,"url":null,"abstract":"Hypoxia is associated with reduced oxygen levels in the body, individual organs, or tissues. Hypoxia is the most common cause of cell damage, emerging under a lack of oxygen in the inhaled air, blood (hypoxemia), or tissues (violations of tissue respiration). When the strength or duration of hypoxic exposure exceeds the adaptive capabilities of the body, an organ, or a tissue, irreversible changes may develop. Resistance to hypoxia can be enhanced by pharmacological agents that improve oxygen delivery and/or the effectiveness of its use. This study was conducted to determine the antihypoxic effect of the Epophen drug. Epophen was found to exhibit a pronounced antihypoxic effect, with the efficacy varying from 24 to 89% depending on the drug dose and hypoxia type.","PeriodicalId":14837,"journal":{"name":"Journal Biomed","volume":"56 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study into the Efficacy of the Epophen Substance in Normobaric Hypoxia\",\"authors\":\"K. Ostrenko, A. Ovcharova, O. P. Yegorova\",\"doi\":\"10.33647/2074-5982-19-2-45-53\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hypoxia is associated with reduced oxygen levels in the body, individual organs, or tissues. Hypoxia is the most common cause of cell damage, emerging under a lack of oxygen in the inhaled air, blood (hypoxemia), or tissues (violations of tissue respiration). When the strength or duration of hypoxic exposure exceeds the adaptive capabilities of the body, an organ, or a tissue, irreversible changes may develop. Resistance to hypoxia can be enhanced by pharmacological agents that improve oxygen delivery and/or the effectiveness of its use. This study was conducted to determine the antihypoxic effect of the Epophen drug. Epophen was found to exhibit a pronounced antihypoxic effect, with the efficacy varying from 24 to 89% depending on the drug dose and hypoxia type.\",\"PeriodicalId\":14837,\"journal\":{\"name\":\"Journal Biomed\",\"volume\":\"56 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal Biomed\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33647/2074-5982-19-2-45-53\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal Biomed","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33647/2074-5982-19-2-45-53","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Study into the Efficacy of the Epophen Substance in Normobaric Hypoxia
Hypoxia is associated with reduced oxygen levels in the body, individual organs, or tissues. Hypoxia is the most common cause of cell damage, emerging under a lack of oxygen in the inhaled air, blood (hypoxemia), or tissues (violations of tissue respiration). When the strength or duration of hypoxic exposure exceeds the adaptive capabilities of the body, an organ, or a tissue, irreversible changes may develop. Resistance to hypoxia can be enhanced by pharmacological agents that improve oxygen delivery and/or the effectiveness of its use. This study was conducted to determine the antihypoxic effect of the Epophen drug. Epophen was found to exhibit a pronounced antihypoxic effect, with the efficacy varying from 24 to 89% depending on the drug dose and hypoxia type.