双相情感障碍患者的治疗依从性及与不依从性相关的信念

E. Uygun, S. Kucukgoncu
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引用次数: 1

摘要

目的:本研究的目的是确定定期使用药物的双相情感障碍患者的治疗依从性,并检查与治疗依从性相关的因素和信念。方法:我们的样本包括92例双相情感障碍患者。采用SCID I情感障碍部分标准对受试者进行诊断和缓解评估,并给出社会人口学数据表、Morisky药物依从性量表(MMAS)和药物依从性信念量表(BMCS)。结果:治疗不依从率为% 29.3。非黏附组与黏附组差异显著的变量为:教育程度低(p=0.03)、导致镇静的药物(p= 0.001)、未接受治疗教育(p= 0.05)、年龄小(p= 0.04)、难以获得药物(p= 0.003)和治疗复杂性(p= 0.01)。特别是用书面/可视化材料训练患者在粘附组更高(p= 0.02)。虽然在BMCS获益量表上没有显著差异(p=0,47),但治疗依从性较差的患者在BMCS屏障量表上的得分明显较高(p=0,01)。在logistic回归分析中,镇静药物、获得药物的困难程度和治疗复杂性是治疗不依从性的显著预测因素。结论:提供药物可及性、使用视觉材料告知处方药物和以患者为中心的方法可提高用药依从性,尤其是在镇静药使用最少的情况下。
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Treatment Adherence in Patients with Bipolar Disorder and Beliefs Related to Non-Adherence
Objective: Our aim in this study was to identify treatment adherence in bipolar disorder patients who regularly use medications and to examine the factors and beliefs associated with treatment compliance. Method: Our sample consisted of 92 patients who were followed up by bipolar disorder. Participants assessed for diagnosis and remission by criteria of affective disorders part of SCID I then Sociodemographic data form, Morisky Medication Adherence Scale (MMAS) and The Beliefs about Medication Compliance Scale (BMCS) was given. Results: Treatment non-adherence rate were %29,3. Variables that differ significantly in non-adherent group then adherent as follows: low education (p=0.03), medications that causes sedation (p=0,001), not educated about treatment (p=0,05), young age (p=0,04), difficulty in obtaining medicine (p=0,003) and treatment complexity (p=0,01). Particularly training the patient with written/visualized materials were higher in adherent group (p=0,02). While there was no significant difference in terms of BMCS benefit subscale (p=0,47), patients with poor treatment compliance reported significantly higher scores on the BMCS barrier subscale (p=0,01). In the logistic regression analysis, sedative medications, difficulty in obtaining medication and treatment complexity were found to be significant predictors of treatment non-adherence. Conclusion: providing access to medication, informing the prescribing medicines with using visual material and patient-centered approaches would increase the compliance of the medication, especially with minimal use of sedative drugs.
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