指外血管球瘤1例

Ashwini Ratnakar, Manasi Gosavi, P. Bhat
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引用次数: 0

摘要

球囊瘤是由球囊小体的平滑肌细胞修饰而成的良性血管肿瘤,占软组织肿瘤的1.6%。在指尖以外的部位出现血管球瘤是非常罕见的。我们报告一个罕见的病例,68岁男性,肩胛间区疼痛结节的历史,过去10年被切除并送到我们的病理科。大体检查,病变大小为1 × 1 cm,结节状。切面呈灰褐色,可见出血区。组织病理学检查显示真皮内有一个界限分明的病变,包括小的扩张的血管间隙,周围有片状和簇状的血管球细胞,细胞核呈圆形,细胞核温和,嗜酸性细胞质中等丰富。无有丝分裂增加,无异型性,无坏死区。无导管/粘蛋白分化区。血管球瘤在指外部位是非常罕见的,并且在临床上可能经常被遗漏。然而,血管周围扁平、均匀的血管球细胞的特征性显微镜图像的存在应该有助于我们得出正确的诊断并为患者提供适当的治疗。
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Extradigital glomus tumor – A rare case report
Glomus tumor is benign vascular tumors arising from modified smooth muscle cells of the glomus bodies and accounting for 1.6% of all soft-tissue tumors. The presence of glomus tumors at sites other than fingertips is a very rare occurrence. We present a rare case of a 68-year-old male with a history of painful nodules over the interscapular region for the last 10 years which was excised and sent to our department of pathology. On gross examination, the lesion was 1 × 1 cm, nodular. Cut section was gray and brown with areas of hemorrhage seen. Histopathological examination revealed a circumscribed lesion in the dermis comprising small dilated vascular spaces surrounded by sheets and clusters of glomus cells having round–oval, bland nucleus with moderate-abundant eosinophilic cytoplasm. No areas with increased mitosis, no atypia, and no necrotic areas were seen. There was no area with ductal/mucin differentiation. Glomus tumor is very rare at extradigital sites and may be often missed clinically. However, the presence of the characteristic microscopic picture of perivascular sheets of bland, uniform glomus cells should help us arrive at the correct diagnosis and provide appropriate management to the patient.
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发文量
23
审稿时长
12 weeks
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