撒哈拉以南非洲的疟疾干预和控制规划:述评

A. Orok, O. Ajibaye, O. Aina, G. Iboma, Sunday Adagyo Oboshi, B. Iwalokun
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引用次数: 7

摘要

摘要:疟疾的传播和流行涉及人、病媒和环境三者之间相互作用的三角网络。控制、消除和/或根除疟疾的任何有意义的努力都应以削弱和/或破坏三角关系中的相互作用为目标。在撒哈拉以南非洲,有效的疟疾控制规划受到无数挑战的阻碍。疟疾负担不减可归因于具有强大生态表达位的高效疟疾媒介在所有季节保持高水平传播。寄生虫的基因型异质性、寄生适应特征的多重表达和不可预测的行为变化是感染因子茁壮成长、持续存在并以令人恐惧的交响乐表达生态位的聪明方式。环境因素和气候变化、人口流动、社会经济状况恶化、无法获得有效和及时的抗疟治疗、使用不合格或假冒抗疟药物、自我用药和不遵守药物剂量是导致干预效果不佳的激励因素。最重要的是,多年来,在大多数环境和社区中,缺乏关于疟疾病原体的知识。转移注意力的因素和误解,如吃太多棕榈油、站在阳光下、喝太多酒、占卜和巫术攻击,都是对疟疾病因和风险因素认识不清的标志。如果在撒哈拉以南非洲实施一千零一项复杂的战略来消除疟疾,在那里,土著和因子的观念与思想的修辞对比占主导地位,那么,一个可预见的失败的表现是预期的结果。为了维持在撒哈拉以南非洲防治疟疾方面已经取得的成果,社区作为促进变革的强有力伙伴的作用不容低估。
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Malaria interventions and control programes in Sub-Saharan Africa: A narrative review
Abstract Abstract: Malaria transmission and prevalence involves a triangular web of interactions between man, vector, and the environment. Any meaningful effort in malaria control, elimination and or eradication should target weakening and or breaking the forces of interactions within the triangle. In sub-Saharan Africa, effective malaria control programme is encumbered by myriad of challenges. The unabated burden of malaria could be ascribed to efficient malaria vectors with strong niche for ecological expression that maintain high levels of transmission at all seasons. Parasite genotypic heterogeneity, multiple expressions of traits of adaptations to parasitism and unpredictable behavioural changes are the smart ways the infectious agent thrives, persists and expresses ecological niche with scaring symphony. Environmental factors and climatic changes, population movement, deteriorated socioeconomic situation, lack of access to effective and timely antimalarial treatment, use of sub-standard and or fake anti-malarial drugs, self medication and non-compliance to drug dosage are the galvanizing factors to poor intervention outcomes. Above all, for ages, in most settings and communities, there is lack of knowledge regarding the causative agent of malaria. Diversionary factors and misconceptions such as eating too much palm oil, standing in the sun, drinking too much of alcohol, jinxing and witchcraft attacks are brands of porous perceptions on causes and risk factors of malaria. And if a thousand and one sophisticated strategies are put in place to eliminate malaria in sub-Saharan Africa where indigenous and factorial perceptions with rhetorical contrast of ideas hold sway, then, a predictable defeated performance is the expected result. For the sustenance of the gains already recorded in the fight against malaria in sub-Saharan Africa, the role of the community as a strong partnership for change cannot be underestimated.
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