植物叶片提取物合成抗尿路感染病原体氧化锌纳米颗粒

J. Santhoshkumar, S. Venkat Kumar, S. Rajeshkumar
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引用次数: 363

摘要

在现代科学中,纳米技术是研究人员的一个热门领域。氧化锌纳米颗粒(ZnO NPs)是一种多功能无机纳米颗粒,在尿路感染的治疗中有着广泛的应用。以西番莲鲜叶提取物为原料合成纳米颗粒,采用紫外可见光谱(UV-vis)、x射线衍射仪(XRD)、傅里叶变换红外光谱(FT-IR)、扫描电镜(SEM)、x射线能谱分析(EDAX)、原子力显微镜(AFM)等对纳米颗粒进行了表征。因此,本研究揭示了一种高效、环保、简单的绿色合成多功能ZnO NPs的方法。从患病患者的尿液样本中分离出引起尿路感染的微生物。合成的纳米颗粒对病原菌的抑制作用较植物提取物明显。这表明ZnO NPs具有良好的生物医学性能。
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Synthesis of zinc oxide nanoparticles using plant leaf extract against urinary tract infection pathogen

In modern science, Nanotechnology is an ablaze field for the researchers. Zinc oxide nanoparticles (ZnO NPs) are known to be one of the most multifunctional inorganic nanoparticles with its application in treatment of urinary tract infection. Nanoparticles were synthesized using Passiflora caerulea fresh leaf extract and were characterized by UV-visible spectroscopy (UV–vis), X-ray diffractometer (XRD), Fourier transform infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM), Energy dispersive analysis of x-ray (EDAX), Atomic force microscopy (AFM). Therefore, the study reveals an efficient, eco-friendly and simple method for the green synthesis of multifunctional ZnO NPs using P. caerulea. Urinary tract infection causing microbes were isolated from the disease affected patient urine sample. The synthesized nanoparticles have been tested against the pathogenic culture showed a very good zone of inhibition compared with plant extract. It indicates the biomedical capability of ZnO NPs.

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