上颌骨肉瘤伴等倍体生长1例

Hirobumi Shoji , Masatoshi Adachi , Hideo Yagishita , Akihiko Shibata , Hisao Yagishita , Masayori Shirakawa , Sadao Okabe
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引用次数: 1

摘要

本文报告一例上颌骨肉瘤,最初被认为是肉芽肿性脓包。45岁男性患者初次检查时发现右上颌磨牙区颊龈有带蒂肿块。临床及病理结果显示肿块为膝外肌。然而,由于快速增大的肿块被临床诊断为上颌肿瘤,我们在全身麻醉下进行了部分上颌切除术。切除标本的病理检查显示,上颌肿瘤为骨肉瘤,部分阳性手术残端。由于术后3年复发,在全麻下行上颌骨全切除。肿瘤侵袭颅底的复发是在再次手术后的2.5年,尽管进行了3个疗程的辅助化疗。给予重粒子放疗。不幸的是,患者在第一次手术后6年零2个月因肿瘤生长和一般情况的逐渐恶化而死亡。本病例的经验表明,早期诊断和适当的手术治疗对于颌骨骨肉瘤的治疗效果是非常重要的。
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A case of maxillary osteosarcoma with epuloid growth

This report presents a case of maxillary osteosarcoma that was initially considered to be granulomatous epulis. A pedunculated mass was found on the buccal gingiva in the right maxillary molar region in a 45-year-old male patient at the initial examination. The clinical and pathological findings indicated that the mass was an epulis. However, a partial maxillectomy was performed under general anesthesia because the rapidly enlarged mass was clinically diagnosed as a maxillary tumor. A pathological examination of the resected specimen revealed that the maxillary tumor was osteosarcoma with a partially positive surgical stump. A total resection of the maxilla was performed under general anesthesia because recurrence was observed at 3 years postoperatively. Recurrence of a tumor that invaded into the cranial base was found at 2.5 years after reoperation despite three courses of adjuvant chemotherapy. Heavy particle radiotherapy was administered. Unfortunately, the patient died at 6 years and 2 months after the first operation due to tumor growth and a gradual worsening of his general condition. The experience from the present case suggested that an early diagnosis and an appropriate surgical therapy is very important for a satisfactory treatment outcomes of the jawbone osteosarcoma.

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